What do systematic reviews say?

Exercise vs usual care

• Exercise therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 136 participants
  Very low

Summary of findings for exercise plus education vs control

• Interventions for preventing falls in Parkinson's disease 2022 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 305 participants
  Very low

Exercise vs control

• Interventions for preventing falls in Parkinson's disease 2022 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 951 participants
  Low

Recombinant human C1 esterase inhibitor vs placebo or active control

The review found no eligible studies for this question.

• Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Chlorhexidine gel (0.12%) vs no treatment

The review found no eligible studies for this question.

• Chlorhexidine treatment for the prevention of dental caries in children and adolescents 2015 · Cochrane All outcomes
  Neither of these trials reported on the other secondary outcomes such as measures of pain, quality of life, patient satisfaction or direct and indirect costs of interventions.
  0 studies
  No studies found

Chlorhexidine varnish vs placebo or no treatment

The review found no eligible studies for this question.

• Chlorhexidine treatment for the prevention of dental caries in children and adolescents 2015 · Cochrane All outcomes
  No trials reported on pain, quality of life, patient satisfaction or costs.
  0 studies
  No studies found

Postnatal pelvic floor muscle training vs control

Postnatal pelvic floor muscle training showed no clear difference in urinary incontinence‐specific quality of life(BFLUTS) compared with control (low certainty).

• Pelvic floor muscle training for preventing and treating urinary and faecal incontinence in antenatal and postnatal… 2020 · Cochrane Headline outcomes only
  MD 1.66
  1 study · 18 participants
  Low

Behavioural intervention vs control

• Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 228 participants
  Moderate
• Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 200 participants
  GRADE not reported

Psychological therapies vs education

• Psychological therapies for the treatment of depression in chronic obstructive pulmonary disease 2019 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 460 participants
  Very low

Summary of findings table ‐ Platelet transfusion vs no platelet transfusion

The review found no eligible studies for this question.

• Use of platelet transfusions prior to lumbar punctures or epidural anaesthesia for the prevention of complications in… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Short‐acting insulin analogues vs regular human insulin

• Short‐acting insulin analogues versus regular human insulin for adult, non‐pregnant persons with type 2 diabetes… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 2 participants
  Very low

Counselling vs usual care

The review found no eligible studies for this question.

• Psychosocial interventions for preventing and treating depression in dialysis patients 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

L‐ornithine L‐aspartate vs placebo or no intervention

• L‐ornithine L‐aspartate for prevention and treatment of hepatic encephalopathy in people with cirrhosis 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low

Summary of findings table ‐ Systemic therapy vs control

• Systemic therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2022 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 147 participants
  Very low

Summary of findings table ‐ Systemic therapy vs control

• Systemic therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 44 participants
  Low

Postnatal pelvic floor muscle training vs control

• Pelvic floor muscle training for preventing and treating urinary and faecal incontinence in antenatal and postnatal… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 170 participants
  GRADE not reported

Intervention not reported

The intervention showed no clear difference in health‐related quality of life (HRQOL) disease‐specific HRQOL (low certainty).

• Positive expiratory pressure therapy versus other airway clearance techniques for bronchiectasis 2017 · Cochrane Headline outcomes only
  no estimate extracted
  17 participants
  Low

Supportive intervention vs control

• Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 294 participants
  Very low

Mixed (BEH/EDU/SUP) intervention vs control

• Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 3012 participants
  Low

Amifostine vs no treatment/placebo

It is very uncertain whether amifostine changes quality of life (Patient Benefit Questionnaire, 10-point scale) compared with no treatment/placebo (very low certainty).

• Pharmacological interventions for preventing dry mouth and salivary gland dysfunction following radiotherapy 2017 · Cochrane All outcomes

  12 months postRT
  MD 0.70 [0.20, 1.20]
  1 study · 180 participants
  Very low