What do systematic reviews say?

Propranolol vs placebo

The review found no eligible studies for this question.

• Early pharmacological interventions for universal prevention of post‐traumatic stress disorder (PTSD) 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Gabapentin vs placebo

The review found no eligible studies for this question.

• Early pharmacological interventions for universal prevention of post‐traumatic stress disorder (PTSD) 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Hydrocortisone vs placebo

The review found no eligible studies for this question.

• Early pharmacological interventions for universal prevention of post‐traumatic stress disorder (PTSD) 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Suprasorb CNP system vs the ABThera system

The review found no eligible studies for this question.

• Negative pressure wound therapy for managing the open abdomen in non‐trauma patients 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

NPWT vs the Bogota bag

The review found no eligible studies for this question.

• Negative pressure wound therapy for managing the open abdomen in non‐trauma patients 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

• Compression therapy for treating post‐thrombotic syndrome 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 32 participants
  Moderate

Pilocarpine vs no treatment/placebo

It is very uncertain whether pilocarpine changes quality of life (McMaster HNRQ, 1-7 scale) compared with no treatment/placebo (very low certainty).

• Pharmacological interventions for preventing dry mouth and salivary gland dysfunction following radiotherapy 2017 · Cochrane All outcomes

  Up to and including 6 months postRT
  MD 0.20 [-0.19, 0.59]
  1 study · 90 participants
  Very low

Doxycycline vs prednisolone

• Interventions for bullous pemphigoid 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 234 participants
  High

Yoga vs an active intervention

• Yoga for treating urinary incontinence in women 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low

Combined HBO and perioperative antibiotics prior to dental implant therapy vs antibiotics alone

• Interventions for preventing osteoradionecrosis of the jaws in adults receiving head and neck radiotherapy 2019 · Cochrane All outcomes

  1 year
  This comparison was only made in 1 study which reported no serious adverse events associated with HBO therapy. Quality of life measures (oral status, functioning, satisfaction) showed emotional functioning and pain…
  1 study · 26 participants
  Very low

Postnatal pelvic floor muscle training vs control

• Pelvic floor muscle training for preventing and treating urinary and faecal incontinence in antenatal and postnatal… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Intervention not reported

• Assistive devices, hip precautions, environmental modifications and training to prevent dislocation and improve… 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 81 participants
  Very low

Yoga vs no specific active intervention

• Yoga for treating urinary incontinence in women 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 18 participants
  Very low

Summary of findings table ‐ Protein vs standard diet

The review found no eligible studies for this question.

• Nutritional interventions for preventing and treating pressure ulcers 2024 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

The intervention showed no clear difference in quality of life: Days of work lost per crisis (moderate certainty).

• Drugs for preventing red blood cell dehydration in people with sickle cell disease 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 145 participants
  Moderate

Yoga vs an active intervention

• Yoga for treating urinary incontinence in women 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low

Professional oral care vs Usual oral care

Professional oral care led to higher change in data on economics and quality of life compared with usual oral care; GRADE not reported.

• Oral care measures for preventing nursing home‐acquired pneumonia 2022 · Cochrane All outcomes

  24 months
  MD 1.5 [0.32, 2.68]
  1 study · 322 participants
  GRADE not reported

Antimicrobial lozenge vs placebo

• Pharmacological interventions for preventing dry mouth and salivary gland dysfunction following radiotherapy 2017 · Cochrane All outcomes

  Over 6 months
  Insufficient evidence of a difference for global quality of life, mouth pain RR 0.94 (95% CI 0.66 to 1.33), sore/burning mouth RR 0.95 (95% CI 0.68 to 1.35), throat pain RR 0.79 (95% CI 0.56 to 1.12) (Duncan 2005)
  1 study
  GRADE not reported

Summary of findings table ‐ Systemic therapy vs control

• Systemic therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2022 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 208 participants
  Very low

Exercise vs usual care

• Exercise therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 123 participants
  Very low