Findings

What do systematic reviews say?

320 questions · 333 findings · 159 reviews

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No studies found 104 · 31.2%GRADE not reported 44 · 13.2%Very low 66 · 19.8%Low 57 · 17.1%Moderate 45 · 13.5%High 17 · 5.1%

Primary health professional‐ and community professional‐led interventions vs enhanced usual care

Quality of life (< 1 month post intervention) ‐ social functioning · adult patients with substance dependence

1 finding from 1 review

Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐ and… 2021 · Cochrane Headline outcomes only
48.36 [41.8, 54.92]
1 study · 155 participants
Very low

Primary comparison for continuous passive motion (CPM) vs no CPM

Quality of life SF‐12. Scale from: 0 to 100 (higher score better). · hospitalised patients who have undergone knee replacement surgery

1 finding from 1 review

Continuous passive motion following total knee arthroplasty in people with arthritis 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 156 participants
Moderate

Summary of findings table ‐ Indicated prevention interventions vs control group

QoL · preventing mental disorders

2 findings from 1 review

Primary‐level and community worker interventions for the prevention of mental disorders and the promotion of… 2023 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 1136 participants
Very low
Primary‐level and community worker interventions for the prevention of mental disorders and the promotion of… 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 152 participants
Very low

Summary of findings table ‐ Promotion/universal prevention interventions vs control group

QoL · preventing mental disorders

2 findings from 1 review

Primary‐level and community worker interventions for the prevention of mental disorders and the promotion of… 2023 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 684 participants
Very low
Primary‐level and community worker interventions for the prevention of mental disorders and the promotion of… 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 803 participants
Low

Summary of findings table ‐ Selective prevention interventions vs control group

QoL · preventing mental disorders

2 findings from 1 review

Primary‐level and community worker interventions for the prevention of mental disorders and the promotion of… 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 115 participants
Very low
Primary‐level and community worker interventions for the prevention of mental disorders and the promotion of… 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 229 participants
Very low

Rehabilitation interventions vs no intervention

Quality of life and participation ‐ mobility and navigation (Analysis 3.1) · stroke survivors with tactile perception disorders

Rehabilitation interventions showed no clear difference in quality of life and participation ‐ mobility and navigation… compared with no treatment or control; GRADE not reported.

1 finding from 1 review

Interventions for perceptual disorders following stroke 2022 · Cochrane Headline outcomes only
MD 6.5
2 studies · 30 participants
GRADE not reported

Selenium vs no intervention

Quality of life and other oral related symptoms (loss of taste, dysphagia) · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region

1 finding from 1 review

Pharmacological interventions for preventing dry mouth and salivary gland dysfunction following radiotherapy 2017 · Cochrane All outcomes
6 weeks after end of RT
Insufficient evidence of differences for loss of taste or dysphagia; data largely unusable (no standard deviations). Ageusia milder in selenium group (not significant); dysphagia significant only at week 7 (P = 0.05)…
1 study
GRADE not reported

Pulmonary rehabilitation vs usual care

Health‐related quality of life Change in total score of St George Respiratory Questionnaire · post‐exacerbation COPD

1 finding from 1 review

Pulmonary rehabilitation following exacerbations of chronic obstructive pulmonary disease 2016 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 1003 participants
High

Intervention not reported

Quality of life (at study completion) EuroQol (VAS) from 0 to 200 mm; higher score means better function · People with hip or knee osteoarthritis

1 finding from 1 review

High‐intensity versus low‐intensity physical activity or exercise in people with hip or knee osteoarthritis 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 214 participants
Very low

Primary health professionals and lay health workers vs usual care

Quality of life (patient) (1 to 6 months post intervention) DEMQOL (higher score = better quality of life) · people with dementia and their carers

1 finding from 1 review

Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐ and… 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 53 participants
Very low

Primary health professionals and lay health workers vs usual care

Carer burden, well‐being or quality of life · people with dementia and their carers

1 finding from 1 review

Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐ and… 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 53 participants
Very low

Rehabilitation interventions vs no intervention

Quality of life and participation ‐ mobility and navigation intervention for not Pusher Syndrome (Analysis 1.2) · stroke survivors with somatosensory perception disorders

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for perceptual disorders following stroke 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Lay health worker‐led psychological interventions vs usual care

Quality of life ‐ intermediate term (1 to 6 months post intervention) EQ‐5Di; SF‐36c,m; WHOQOL‐BREFe,j,n (higher score = better quality of life) · adults with post‐traumatic stress and CMDs

1 finding from 1 review

Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐ and… 2021 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 1918 participants
Moderate

Lay health worker‐led psychological interventions vs usual care

Quality of life ‐ intermediate term (1 to 6 months post intervention) EQ‐5Di; SF‐36c,m; WHOQOL‐BREFe,j,n (higher score = better quality of life) · adults with common mental disorders

1 finding from 1 review

Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐ and… 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 521 participants
Low

Primary health professional‐led or collaborative care vs usual or enhanced care

Quality of life ‐ intermediate term (1 to 6 months post intervention) SF‐36 social functioning (higher score = higher quality of life) · women with perinatal depression

It is very uncertain whether primary health professional‐led collaborative care interventions changes quality of life ‐ intermediate term (1 to 6 months post… compared with usual or enhanced care (very low certainty).

1 finding from 1 review

Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐ and… 2021 · Cochrane Headline outcomes only
MD 3.5
1 study · 230 participants
Very low

Primary‐level worker‐led collaborative care vs usual care

Quality of life ‐ intermediate term (1 to 6 months post intervention) EQ‐5Di; SF‐36c,m; WHOQOL‐BREFe,j,n (higher score = better quality of life) · adults with common mental disorders

1 finding from 1 review

Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐ and… 2021 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 2199 participants
Low

Primary health professionals and lay health workers vs usual care

Mental distress · people with dementia and their carers

1 finding from 1 review

Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐ and… 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 134 participants
Low

Dalteparin vs placebo

Quality of life (e.g. absence from school, lost time at work, mobility) as assessed by any validated questionnaire either generic or SCD specific) ‐ not measured · sickle cell disease

The review found no eligible studies for this question.

1 finding from 1 review

Low‐molecular‐weight heparins for managing vaso‐occlusive crises in people with sickle cell disease 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Tinzaparin vs placebo

Quality of life (e.g. absence from school, lost time at work, mobility) as assessed by any validated questionnaire either generic or SCD specific) ‐ not measured · people with sickle cell disease

The review found no eligible studies for this question.

1 finding from 1 review

Low‐molecular‐weight heparins for managing vaso‐occlusive crises in people with sickle cell disease 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Health‐related quality of life Multiple different outcome measures used EQ‐5D and EQ‐5D VAS (9 and 26 weeks) (Batterham 2014) SF‐36 PCS and MCS (8 and 26 weeks) (Elliott 2011) · adult survivors of critical illness

1 finding from 1 review

Exercise rehabilitation following intensive care unit discharge for recovery from critical illness 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 2 participants
Very low