What do systematic reviews say?

Summary of Findings Table ‐ Large retro‐equatorial recession of horizontal rectus muscle of 9 mm on the medial rectus and 12 mm on the lateral rectus vs simple tenotomy and resuturing of the 4 horizontal rectus muscles

• Surgical interventions for infantile nystagmus syndrome 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 10 participants
  Very low

Summary of findings table ‐ Physiotherapeutic scoliosis‐specific exercises (PSSE) vs general therapeutic exercises (GTE)

• Therapeutic exercises for idiopathic scoliosis in adolescents 2024 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 168 participants
  Very low

Summary of findings: oral antioxidant combination vs control

The review found no eligible studies for this question.

• Antioxidant supplementation for lung disease in cystic fibrosis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings table ‐ Daratumumab plus standard therapy vs usual care

• Daratumumab and antineoplastic therapy versus antineoplastic therapy only for adults with newly diagnosed multiple… 2024 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 1096 participants
  Low

Summary of findings: Inhaled antibiotics plus IV antibiotics vs IV antibiotics

Summary of findings: Inhaled antibiotics plus IV antibiotics showed no clear difference in quality of life: number of participants achieving MCID compared with IV antibiotics only (low certainty).

• Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis 2022 · Cochrane Headline outcomes only
  RR 1.2 [0.61, 2.34]
  1 study · 16 participants
  Low

Summary of findings table ‐ Protein, arginine, zinc and antioxidants vs standard diet or placebo

The review found no eligible studies for this question.

• Nutritional interventions for preventing and treating pressure ulcers 2024 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings: Restitutive interventions vs control

It is very uncertain whether summary of findings: Restitutive interventions changes quality of life (improved or not improved ‐ derived from percentage… compared with control (very low certainty).

• Interventions for visual field defects in people with stroke 2019 · Cochrane Headline outcomes only
  OR 13 [2.07, 81.48]
  1 study · 30 participants
  Very low

Summary of findings table ‐ Rehabilitation‐related activity interventions vs usual care with or without sham interventions

• Exercise for acutely hospitalised older medical patients 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 350 participants
  GRADE not reported

Summary of findings table ‐ Progressive resistance exercise interventions vs usual care with or without sham interventions

• Exercise for acutely hospitalised older medical patients 2022 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 449 participants
  Moderate

Summary of findings: Compensative interventions vs control

Summary of findings: Compensative interventions may leads to higher quality of life (National Eye Institute Visual Function… compared with control (low certainty).

• Interventions for visual field defects in people with stroke 2019 · Cochrane Headline outcomes only
  MD 9.36 [3.1, 15.62]
  2 studies · 96 participants
  Low

Summary of Findings Table ‐ The Lidcombe Program vs waiting list control

• Non‐pharmacological interventions for stuttering in children six years and younger 2021 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Minoxidil vs placebo

The review found no eligible studies for this question.

• Treatments for alopecia areata: a network meta‐analysis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings table ‐ Oral small molecule inhibitors (ruxolitinib) vs oral small molecule inhibitors (tofacitinib)

The review found no eligible studies for this question.

• Treatments for alopecia areata: a network meta‐analysis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings table ‐ Topical small molecule inhibitors (ruxolitinib) vs placebo

The review found no eligible studies for this question.

• Treatments for alopecia areata: a network meta‐analysis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings for the main comparison. Physical activity and exercise interventions vs usual care

• Physical activity interventions for people with congenital heart disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 163 participants
  Very low

Summary of findings: aztreonam lysine for inhalation vs tobramycin

• Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 268 participants
  Moderate

Summary of findings table ‐ Oral classical immunosuppressants (betamethasone) vs oral classical immunosuppressants (azathioprine, methotrexate, prednisolone)

The review found no eligible studies for this question.

• Treatments for alopecia areata: a network meta‐analysis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings for cholinesterase inhibitors vs placebo

• Interventions for preventing falls in Parkinson's disease 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 121 participants
  Very low

Summary of findings table ‐ Oral classical immunosuppressants (prednisolone or cyclosporine) vs placebo

• Treatments for alopecia areata: a network meta‐analysis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 36 participants
  Very low

Summary of findings ‐ dual therapy: tezacaftor plus ivacaftor vs placebo or ivacaftor alone

• Corrector therapies (with or without potentiators) for people with cystic fibrosis with class II CFTR gene variants… 2023 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 946 participants
  Low