Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

16 questions · 16 findings · 6 reviews

No studies found 10 · 62.5%GRADE not reported 0 · 0%Very low 2 · 12.5%Low 2 · 12.5%Moderate 2 · 12.5%High 0 · 0%

Summary of findings ‐ triple therapy: elexacaftor‐tezacaftor‐ivacaftor vs control (ivacaftor alone or tezacaftor plus ivacaftor)

Quality of life: total score · adults and children aged 12 years and over with cystic fibrosis and either F508del/gating variant or F508del/residual function genotype

The review found no eligible studies for this question.

1 finding from 1 review

Summary of findings ‐ triple therapy: elexacaftor‐tezacaftor‐ivacaftor/deutivacaftor vs control

Quality of life: total score · adults with cystic fibrosis and either F508del/MF or F508del/F508del genotype

The review found no eligible studies for this question.

1 finding from 1 review

Physiotherapy and occupational therapy vs placebo

Short‐term (1 week) change in quality of life scores related to communication as measured by validated communication assessments Functional Independence Measure (total). Scale from: 0 to 126. Higher scores indicate less disability · people with speech disorder resulting from hereditary ataxias
1 finding from 1 review

Intervention not reported

Total quality of life score over 12 weeks Assessed as the total score over the entire 12‐week study period in the Juniper RQLQ, i.e. a patient‐specific test instrument derived from 28 questions drawn from 7 dimensions (sleep, non‐hay fever symptom... · patients with allergic rhinitis1
1 finding from 1 review