Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

66 questions · 67 findings · 24 reviews · Musculoskeletal

No studies found 11 · 16.4%GRADE not reported 1 · 1.5%Very low 12 · 17.9%Low 33 · 49.3%Moderate 8 · 11.9%High 2 · 3%

Autologous blood or PRP vs placebo at 3 months' follow‐up

Adverse events (pain and swelling at injection site and limitation of elbow movement following injection) · lateral elbow pain

Autologous blood or PRP showed no clear difference in adverse events (pain and swelling at injection site and limitation… compared with placebo at 3 months' follow‐up (low certainty).

1 finding from 1 review

Low‐dose colchicine vs placebo

Participant global assessment of treatment success: proportion with 50% or greater decrease in pain score from baseline ‐ 32 to 36 hours · acute gout

Low‐dose colchicine may leads to higher participant global assessment of treatment success: proportion with… compared with placebo (low certainty).

1 finding from 1 review

Intervention not reported

Pain 10‐point VAS (lower score reflects better outcome) · people with neurological conditions1
1 finding from 1 review

Intervention not reported

Pain 10‐point VAS (lower score reflects better outcome) · people with non‐neurological conditions1
1 finding from 1 review