Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

74 questions · 80 findings · 28 reviews

No studies found 23 · 28.8%GRADE not reported 0 · 0%Very low 26 · 32.5%Low 26 · 32.5%Moderate 4 · 5%High 1 · 1.3%

Summary of findings table ‐ Progestogens vs placebo or no pretreatment

Multiple pregnancy rate · ovarian stimulation protocols for women undergoing ART

The review found no eligible studies for this question.

2 findings from 1 review

Combined oral contraceptive pill vs no pretreatment

Multiple pregnancy rate · women undergoing assisted reproduction

Combined oral contraceptive pill showed no clear difference in multiple pregnancy rate (COCP + Ant vs Ant) compared with no pretreatment (low certainty).

2 findings from 1 review

Oestrogen vs no pretreatment

Multiple pregnancy rate · ovarian stimulation protocols for women undergoing ART

The review found no eligible studies for this question.

2 findings from 1 review

IVF vs unstimulated IUI

Multiple pregnancy rate · women with unexplained subfertility

It is very uncertain whether IVF changes multiple pregnancy rate per woman randomised compared with unstimulated IUI (very low certainty).

1 finding from 1 review

Intervention not reported

Multiple pregnancy ‐ Clomiphene citrate 5 days versus clomiphene citrate 10 days · ovulation induction in polycystic ovarian syndrome

It is very uncertain whether the intervention changes multiple pregnancy ‐ Clomiphene citrate 5 days versus clomiphene… (very low certainty).

1 finding from 1 review