Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

7 questions · 7 findings · 7 reviews · Emergency and Critical Care

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 3 · 42.9%Low 3 · 42.9%Moderate 1 · 14.3%High 0 · 0%

Intervention not reported

Mortality at longest · adult (≥ 18 years of age) patients receiving mechanical ventilation (via either an endotracheal tube or a tracheostomy) for acute…

It is very uncertain whether the intervention changes mortality at longest (very low certainty).

1 finding from 1 review

Thromboelastography (TEG) or thromboelastometry (ROTEM) vs any comparison

Mortality within the longest · adults or children with bleeding

Thromboelastography (TEG) or thromboelastometry (ROTEM) may leads to lower mortality longest compared with any comparison (low certainty).

1 finding from 1 review

Summary of findings table ‐ Prothrombin complex concentrates vs any comparator

Mortality within the longest · patients with vitamin K antagonist‐induced bleeding requiring acute intervention

It is very uncertain whether prothrombin complex concentrate changes overall mortality ‐ longest compared with any comparator (very low certainty).

1 finding from 1 review

Omega‐3 fatty acids and antioxidants vs standard diet or placebo

Mortality within the longest · adults (aged 18 years or older), mechanically ventilated participants with ARDS as defined by the Berlin definition of ARDS or, for older…

Omega‐3 fatty acids and antioxidants showed no clear difference in all‐cause mortality (longest period reported) compared with placebo or standard nutrition (low certainty).

1 finding from 1 review

Physical and cognitive therapy vs usual care

In‐hospital mortality at 30 days or at the longest · critically ill patients 18 years or older treated for respiratory failure or septic or both, cardiogenic or haemorrhagic shock who resided…

It is very uncertain whether physical and cognitive therapy changes in‐hospital mortality at 30 days or at the longest compared with standard care (very low certainty).

1 finding from 1 review