Cochrane · systematic review · CD013708
Oxygen targets in the intensive care unit during mechanical ventilation for acute respiratory distress syndrome: a rapid review
Cumpstey, AF, Oldman, AH, Smith, AF, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
Emergency and Critical CareAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 1 · 20%Very low 4 · 80%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Oxygen targets in the intensive care unit during mechanical ventilation for acute respiratory distress syndrome
Population: adult (≥ 18 years of age) patients receiving mechanical ventilation (via either an endotracheal tube or a tracheostomy) for acute respiratory distress syndrome (ARDS) (Berlin definition), including ARDS secondary to COVID‐19 or other viruses
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality at longest | OR 1.83 [1.03, 3.27] | 1 study · 201 participants | Very low Downgraded: risk of bias, imprecision |
Number of days ventilated | no estimate extracted | 1 study · 201 participants | Very low Downgraded: risk of bias, imprecision |
Requirement for inotropic support (scale from 0 to 28, days of catecholamine use) | no estimate extracted | 1 study · 201 participants | Very low Downgraded: risk of bias, imprecision |
Requirement for renal replacement therapy ( | OR 1.03 [0.41, 2.6] | 1 study · 201 participants | Very low Downgraded: risk of bias, imprecision |
Quality of life | no estimate extracted | 0 participants | Ungraded |