Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

14 questions · 14 findings · 11 reviews · Headline outcomes only

No studies found 1 · 7.1%GRADE not reported 2 · 14.3%Very low 4 · 28.6%Low 5 · 35.7%Moderate 2 · 14.3%High 0 · 0%

Single‐component medication monitoring and adjustment intervention vs control

All‐cause mortality · people at risk of delirium in institutional long‐term care

Single‐component medication monitoring and adjustment intervention showed no clear difference in mortality compared with control (moderate certainty).

1 finding from 1 review

Standard‐dose VKA plus single antiplatelet agent vs vitamin K antagonist (VKA)

Total mortalitya · people with antiphospholipid syndrome and a history of stroke or thromboembolic events

It is very uncertain whether standard‐dose VKA plus single antiplatelet agent changes all‐cause mortalitya compared with standard‐dose VKA (very low certainty).

1 finding from 1 review

Single component intervention vs control

Adverse events: number of people experiencing adverse events (all cause or COPD‐related), serious adverse events, mortality · COPD

It is very uncertain whether single component intervention changes adverse events: number of people experiencing adverse events (all… compared with control (very low certainty).

1 finding from 1 review