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Evidence found and GRADE certainty

23 questions · 29 findings · 8 reviews · Neonatal

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No studies found 3 · 10.3%GRADE not reported 2 · 6.9%Very low 8 · 27.6%Low 9 · 31%Moderate 7 · 24.1%High 0 · 0%

Comparison 1: antibiotic alone or antibiotic with other newborn care interventions vs usual care

Neonatal mortality · neonates with sepsis

Comparison 1: antibiotic alone or antibiotic with other newborn care… showed no clear difference in neonatal mortality ‐ antibiotics alone compared with standard care (moderate certainty).

2 findings from 1 review

Community health educational intervention for family members and mothers and for mothers only (subgroup) vs control

Neonatal mortality ‐ Intervention given to mothers only · developing countries

It is very uncertain whether community health educational intervention for family members and… changes neonatal mortality ‐ Intervention given to mothers only compared with control (very low certainty).

1 finding from 1 review

Community health educational intervention for family members and mothers and for mothers only (subgroup) vs control

Perinatal mortality · developing countries

Community health educational intervention for family members and… may leads to lower perinatal mortality ‐ Intervention given to mothers and family members compared with control (low certainty).

2 findings from 1 review

Community health educational intervention for family members and mothers and for mothers only (subgroup) vs control

Late neonatal mortality ‐ Intervention given to mothers only · developing countries

It is very uncertain whether community health educational intervention for family members and… changes late neonatal mortality ‐ Intervention given to mothers only compared with control (very low certainty).

1 finding from 1 review

Community health educational intervention for family members and mothers and for mothers only (subgroup) vs control

Early neonatal mortality ‐ Intervention given to mothers only · developing countries

It is very uncertain whether community health educational intervention for family members and… changes early neonatal mortality ‐ Intervention given to mothers only compared with control (very low certainty).

1 finding from 1 review

Community health educational intervention for family members and mothers and for mothers only (subgroup) vs control

Neonatal mortality · developing countries

Community health educational intervention for family members and… may leads to lower neonatal mortality ‐ Intervention given to mothers and family members compared with control (low certainty).

1 finding from 1 review

Community health educational intervention for family members and mothers and for mothers only (subgroup) vs control

Late neonatal mortality ‐ Intervention given to mothers and family members · developing countries

Community health educational intervention for family members and… may leads to lower late neonatal mortality ‐ Intervention given to mothers and family… compared with control (low certainty).

1 finding from 1 review

Community health educational intervention for family members and mothers and for mothers only (subgroup) vs control

Early neonatal mortality ‐ Intervention given to mothers and family members · developing countries

It is very uncertain whether community health educational intervention for family members and… changes early neonatal mortality ‐ Intervention given to mothers and family… compared with control (very low certainty).

1 finding from 1 review

Community health educational interventions vs control

Neonatal mortality · developing countries

Community health educational interventions may leads to lower neonatal mortality compared with control (low certainty).

2 findings from 1 review

Community health educational interventions vs control

Perinatal mortality · developing countries

Community health educational interventions probably leads to lower perinatal mortality compared with control (moderate certainty).

2 findings from 1 review

Community health educational interventions vs control

Late neonatal mortality · developing countries

It is very uncertain whether community health educational interventions changes late neonatal mortality compared with control (very low certainty).

2 findings from 1 review

Community health educational interventions vs control

Early neonatal mortality · developing countries

It is very uncertain whether community health educational interventions changes early neonatal mortality compared with control (very low certainty).

2 findings from 1 review

Moderate vs low protein concentration of human milk fortifier

Mortality during period of therapy · preterm infants

Moderate showed no clear difference in mortality during the intervention period compared with low protein concentration of human milk fortifier; GRADE not reported.

1 finding from 1 review

Enteral zinc supplementation vs no zinc supplementation

All‐cause mortality (between start of intervention and end of · preterm infants

Enteral zinc supplementation may leads to lower all‐cause mortality (between start of intervention and end of compared with no zinc supplementation (low certainty).

1 finding from 1 review

Pentoxifylline with antibiotics (any dose or duration) vs placebo or no intervention

All‐cause mortality during hospital stay · neonates with sepsis

Pentoxifylline with antibiotics (any dose or duration) may leads to lower all‐cause mortality during hospital stay compared with placebo or no intervention (low certainty).

1 finding from 1 review