Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

559 questions · 576 findings · 177 reviews

No studies found 140 · 24.3%GRADE not reported 45 · 7.8%Very low 184 · 31.9%Low 131 · 22.7%Moderate 60 · 10.4%High 16 · 2.8%

Band ligation vs no intervention or a sham procedure

All‐cause mortality · children with portal hypertension and large oesophageal varices, without previous gastrointestinal bleeding or beta‐blocker treatment

It is very uncertain whether band ligation changes all‐cause mortality compared with sham or no intervention (very low certainty).

1 finding from 1 review

Portosystemic shunts vs endoscopic intervention with or without medical treatment

All‐cause mortality · participants with cirrhosis and with previous oesophagogastric variceal bleeding

It is very uncertain whether portosystemic shunts changes all‐cause mortality compared with endoscopic intervention with or without medical treatment (very low certainty).

1 finding from 1 review

Distal splenorenal shunt vs endoscopic intervention

All‐cause mortality · participants with cirrhosis and with previous oesophagogastric variceal bleeding

It is very uncertain whether distal splenorenal shunt changes all‐cause mortality compared with endoscopic intervention (very low certainty).

1 finding from 1 review

Transjugular intrahepatic portosystemic shunts vs endoscopic intervention with or without medical treatment

All‐cause mortality · participants with cirrhosis and with previous oesophagogastric variceal bleeding

It is very uncertain whether transjugular intrahepatic portosystemic shunt changes all‐cause mortality compared with endoscopic intervention with or without medical treatment (very low certainty).

1 finding from 1 review

Total shunt vs endoscopic intervention

All‐cause mortality · participants with cirrhosis and with previous oesophagogastric variceal bleeding

It is very uncertain whether total shunt changes all‐cause mortality compared with endoscopic intervention (very low certainty).

1 finding from 1 review

Sclerotherapy vs no intervention

All‐cause mortality · primary prophylaxis of oesophageal variceal bleeding in children with chronic liver disease or portal vein thrombosis

It is very uncertain whether sclerotherapy changes all‐cause mortality compared with no intervention (very low certainty).

1 finding from 1 review