Findings

What do systematic reviews say?

9 questions · 9 findings · 6 reviews · Heart

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No studies found 1 · 11.1%GRADE not reported 0 · 0%Very low 4 · 44.4%Low 2 · 22.2%Moderate 2 · 22.2%High 0 · 0%

High vs low blood pressure target

All‐cause mortality · adults undergoing cardiac surgery with cardiopulmonary bypass

It is very uncertain whether high changes all‐cause mortality compared with low blood pressure target (very low certainty).

1 finding from 1 review

High versus low blood pressure targets for cardiac surgery while on cardiopulmonary bypass 2022 · Cochrane Headline outcomes only
RR 1.33 [0.3, 5.9]
3 studies · 737 participants
Very low

Any glucocorticoid vs placebo

Mortality within the longest · Children having heart surgery with cardiopulmonary bypass

Glucocorticoid showed no clear difference in all‐cause mortality at longest compared with placebo (moderate certainty).

1 finding from 1 review

Prophylactic corticosteroids for paediatric heart surgery with cardiopulmonary bypass 2020 · Cochrane Headline outcomes only
RR 0.83 [0.33, 2.07]
5 studies · 313 participants
Moderate

Systematic screening vs no/opportunistic screening

All‐cause mortality · general population including those at moderate to high risk of CVD, mean age between 30 and 75

Systematic screening showed no clear difference in all‐cause mortality compared with no/opportunistic screening (low certainty).

1 finding from 1 review

Systematic versus opportunistic risk assessment for the primary prevention of cardiovascular disease 2016 · Cochrane Headline outcomes only
RR 0.98 [0.93, 1.03]
3 studies · 103571 participants
Low

Colchicine vs any control treatment

Mortality (all‐cause) · any patient population and people with high cardiovascular risk

Colchicine showed no clear difference in mortality (all‐cause) compared with any control treatment (moderate certainty).

1 finding from 1 review

Colchicine for prevention of cardiovascular events 2016 · Cochrane Headline outcomes only
RR 0.94 [0.82, 1.09]
30 studies · 4174 participants
Moderate

Prophylactic corticosteroids vs placebo or no corticosteroids

Mortality within the longest · adults diagnosed with coronary artery disease or cardiac valve disease, and candidates for cardiac surgery with cardiopulmonary bypass

Prophylactic corticosteroids showed no clear difference in all‐cause mortality (during the index hospital admission, or within… compared with placebo or no corticosteroids (low certainty).

1 finding from 1 review

Prophylactic corticosteroids for cardiopulmonary bypass in adult cardiac surgery 2024 · Cochrane Headline outcomes only
RR 0.9 [0.75, 1.07]
25 studies · 14940 participants
Low

Pharmacological treatment vs placebo

All‐cause mortality ‐ short term · health problem or population

It is very uncertain whether summary of findings table ‐ Pharmacological treatment changes all‐cause mortality ‐ short term compared with placebo (very low certainty).

1 finding from 1 review

Psychological and pharmacological interventions for depression in patients with coronary artery disease 2021 · Cochrane Headline outcomes only
OR 0.38 [0.1, 1.47]
2 studies · 437 participants
Very low

Summary of findings table ‐ Psychological interventions vs control

All‐cause mortality ‐ short‐term · health problem or population

It is very uncertain whether summary of findings table ‐ Psychological treatment changes all‐cause mortality ‐ short‐term compared with control (very low certainty).

1 finding from 1 review

Psychological and pharmacological interventions for depression in patients with coronary artery disease 2021 · Cochrane Headline outcomes only
OR 0.31 [0.05, 2.02]
2 studies · 324 participants
Very low

Pharmacological treatment vs pharmacological treatment 2

All‐cause mortality ‐ short term (end of treatment) · health problem or population

It is very uncertain whether summary of findings table ‐ Pharmacological treatment 1 changes all‐cause mortality ‐ short term (end of treatment) compared with pharmacological treatment 2 (very low certainty).

1 finding from 1 review

Psychological and pharmacological interventions for depression in patients with coronary artery disease 2021 · Cochrane Headline outcomes only
OR 2.72 [0.51, 14.49]
1 study · 149 participants
Very low

Psychological interventions vs psychological treatment

All‐cause mortality ‐ short term (end of treatment) ‐ not reported · health problem or population

The review found no eligible studies for this question.

1 finding from 1 review

Psychological and pharmacological interventions for depression in patients with coronary artery disease 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found