IVF vs expectant management
It is very uncertain whether IVF changes live birth per woman randomised compared with expectant management (very low certainty).
- OR 22 [2.56, 189.37]1 study · 51 participantsVery low
It is very uncertain whether IVF changes live birth per woman randomised compared with expectant management (very low certainty).
IVF showed no clear difference in live birth rate per woman randomised compared with IUI + ovarian stimulation with gonadotropins or CC (low certainty).
IVF may leads to higher live birth rate per woman randomised compared with unstimulated IUI (low certainty).
Natural cycle IVF showed no clear difference in live birth per woman compared with standard IVF (moderate certainty).
It is very uncertain whether day 3 changes live birth rate per woman compared with day 2 embryo transfer following IVF or ICSI (very low certainty).
The review found no eligible studies for this question.
Clomiphene citrate or letrozole with or without gonadotropins (with… showed no clear difference in live birth per woman compared with gonadotropins (with GnRH agonist or midcycle antagonist) (low certainty).
RhCG showed no clear difference in ongoing pregnancy/live birth rate per woman compared with uhCG (moderate certainty).
It is very uncertain whether rhLH changes ongoing pregnancy/live birth rate per woman compared with uhCG (very low certainty).
Clomiphene citrate or letrozole with or without gonadotropins (with… showed no clear difference in live birth per woman compared with gonadotropins (with GnRH agonists or midcycle antagonist) (low certainty).
Assisted hatching showed no clear difference in live births per woman randomised compared with no assisted hatching (low certainty).
Ultrasound‐guided embryo transfer may leads to higher live birth and ongoing pregnancy (per woman randomised) compared with clinical touch (low certainty).
It is very uncertain whether adjuvant growth hormone changes live birth rate per woman randomised compared with no adjuvant: routine use (very low certainty).
It is very uncertain whether adjuvant growth hormone changes live birth rate per woman randomised compared with no adjuvant: poor responders (very low certainty).
Metformin showed no clear difference in live birth rate per woman ‐ long protocol GnRH‐agonist compared with placebo or no treatment (low certainty).
Metformin may leads to lower live birth rate per woman ‐ short protocol GnRH‐antagonist compared with placebo or no treatment (low certainty).
Endometrial injury showed no clear difference in live birth per woman randomised (studies at low risk of selection… compared with control (moderate certainty).
It is very uncertain whether higher changes live birth per woman randomised: sensitivity analysis (including all… compared with lower degree of injury (very low certainty).