Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

44 questions · 47 findings · 28 reviews

No studies found 6 · 12.8%GRADE not reported 1 · 2.1%Very low 11 · 23.4%Low 24 · 51.1%Moderate 5 · 10.6%High 0 · 0%

Clomiphene citrate or letrozole with or without gonadotropins (with or without midcycle antagonist) vs gonadotropins (with GnRH agonists or midcycle antagonist)

Live birth rate per woman · Women undergoing controlled ovarian stimulation in IVF and ICSI cycles (poor responders)

Clomiphene citrate or letrozole with or without gonadotropins (with… showed no clear difference in live birth per woman compared with gonadotropins (with GnRH agonist or midcycle antagonist) (low certainty).

1 finding from 1 review

Repeated single embryo transfer (mixed policies) vs multiple embryo transfer

Cumulative live birth · transfer following in vitro fertilisation or intracytoplasmic sperm injection

Repeated single embryo transfer (mixed policies) showed no clear difference in cumulative live birth compared with multiple embryo transfer (low certainty).

1 finding from 1 review

Clomiphene citrate or letrozole with or without gonadotropins (with or without midcycle antagonist) vs gonadotropins (with GnRH agonists or midcycle antagonist)

Live birth rate per woman · for controlled ovarian stimulation

Clomiphene citrate or letrozole with or without gonadotropins (with… showed no clear difference in live birth per woman compared with gonadotropins (with GnRH agonists or midcycle antagonist) (low certainty).

1 finding from 1 review

Ultrasound‐guided embryo transfer vs clinical touch

Ongoing pregnancy / live birth rate per woman · Women undergoing embryo transfer as part of IVF or ICSI cycle

Ultrasound‐guided embryo transfer may leads to higher live birth and ongoing pregnancy (per woman randomised) compared with clinical touch (low certainty).

1 finding from 1 review