Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

12 questions · 12 findings · 7 reviews · Schizophrenia

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 5 · 41.7%Low 6 · 50%Moderate 1 · 8.3%High 0 · 0%

Magnetic seizure therapy plus standard care vs electroconvulsive therapy plus standard care

Dropout · people with the acute phase of schizophrenia

It is very uncertain whether magnetic seizure therapy plus standard care changes leaving the study early: any reasonassessed by: number of dropouts… compared with electroconvulsive therapy plus standard care (very low certainty).

1 finding from 1 review

COGNITIVE REMEDIATION THERAPY (CRG) + TREATMENT‐AS‐USUAL (TAU) vs TAU

Leaving the study early · Adolescents with psychosis

It is very uncertain whether COGNITIVE REMEDIATION THERAPY (CRG) + TREATMENT‐AS‐USUAL (TAU) changes leaving the study early: For any reason compared with TAU (all short‐term) (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Cognitive behavioural therapy plus standard care vs control

Leaving the study early ‐ for any reason ‐ overall acceptability (combined time points) · recent‐onset psychosis (less than three years since the start of psychotic symptoms and either first or second psychotic episode)

Summary of findings table ‐ Cognitive behavioural therapy plus… showed no clear difference in leaving the study early ‐ for any reason ‐ overall acceptability… compared with control (moderate certainty).

1 finding from 1 review

PSYCHOEDUCATIONAL (PE) + MULTIFAMILY TREATMENT (MFT) vs NONSTRUCTURED GROUP THERAPY (NSGT, all long‐term)

Leaving the study early · Adolescents with psychosis

PSYCHOEDUCATIONAL (PE) + MULTIFAMILY TREATMENT (MFT) showed no clear difference in leaving the study early: For any reason compared with NONSTRUCTURED GROUP THERAPY (NSGT, all long‐term) (low certainty).

1 finding from 1 review

CBT vs ALL OTHER PSYCHOLOGICAL THERAPIES

Satisfaction with treatment: leaving the study early Endpoint data (events) · patients with schizophrenia

CBT may leads to lower satisfaction with treatment ‐ leaving the study early for any reason compared with ALL OTHER PSYCHOLOGICAL THERAPIES (low certainty).

1 finding from 1 review

Summary of findings table ‐ CBT without antipsychotics vs CBT plus antipsychotics

Leaving the study early/ loss to · schizophrenia

It is very uncertain whether summary of findings table ‐ CBT without antipsychotics changes leaving the study early ‐ for any reason ‐ overall acceptability… compared with CBT plus antipsychotics (very low certainty).

1 finding from 1 review

Summary of findings table ‐ CBT without antipsychotics vs no specific treatment

Leaving the study early/ loss to · schizophrenia

Summary of findings table ‐ CBT without antipsychotics showed no clear difference in leaving the study early ‐ for any reason ‐ overall acceptability… compared with no specific treatment (low certainty).

1 finding from 1 review

Summary of findings table ‐ CBT without antipsychotics vs antipsychotics

Leaving the study early/ loss to · schizophrenia

It is very uncertain whether summary of findings table ‐ CBT without antipsychotics changes leaving the study early ‐ for any reason ‐ overall acceptability… compared with antipsychotics (very low certainty).

1 finding from 1 review