What do systematic reviews say?

Summary of findings table ‐ Topical small molecule inhibitors (ruxolitinib) vs placebo

The review found no eligible studies for this question.

• Treatments for alopecia areata: a network meta‐analysis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings table ‐ Contact immunotherapy (diphencyprone or squaric acid dibutil ester) vs placebo

The review found no eligible studies for this question.

• Treatments for alopecia areata: a network meta‐analysis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Minoxidil vs placebo

The review found no eligible studies for this question.

• Treatments for alopecia areata: a network meta‐analysis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

NB‐UVB vs placebo

The review found no eligible studies for this question.

• Phototherapy for atopic eczema 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Methotrexate vs placebo

The review found no eligible studies for this question.

• Methotrexate for psoriatic arthritis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Paliperidone palmitate vs placebo

The review found no eligible studies for this question.

• Paliperidone palmitate for schizophrenia 2012 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Anti‐IgE mAb (omalizumab) vs placebo (on top of topical steroids)

• Biologics for chronic rhinosinusitis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 38 participants
  Very low

Moisturisers vs vehicle, placebo or no moisturiser

• Emollients and moisturisers for eczema 2017 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 300 participants
  Low

Selenium (+LT4) vs placebo (+LT4)

The review found no eligible studies for this question.

• Selenium supplementation for Hashimoto's thyroiditis 2013 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings table ‐ Cannabis vs placebo

• Cannabis and cannabinoids for symptomatic treatment for people with multiple sclerosis 2022 · Cochrane Headline outcomes only
  no estimate extracted
  8 studies · 1942 participants
  Low

Pregabalin vs placebo

• Pregabalin for decreasing pancreatic pain in chronic pancreatitis 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 64 participants
  Moderate

SPRM vs placebo

• Selective progesterone receptor modulators (SPRMs) for uterine fibroids 2017 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 200 participants
  Moderate

Spironolactone 100 mg vs placebo

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Finasteride 5 mg to 7.5 mg vs placebo

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Metformin 500 mg to 2550 mg per day vs placebo

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Flutamide 250 mg b.i.d. vs placebo

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Mepolizumab intravenous (IV) vs placebo

• Anti‐IL‐5 therapies for asthma 2022 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 369 participants
  High

Mepolizumab subcutaneous (SC) vs placebo

• Anti‐IL‐5 therapies for asthma 2022 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 1231 participants
  High

Benralizumab subcutaneous (SC) vs placebo

• Anti‐IL‐5 therapies for asthma 2022 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 2791 participants
  High

Urea‐containing moisturisers vs vehicle, placebo or no moisturiser

The review found no eligible studies for this question.

• Emollients and moisturisers for eczema 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found