Findings

What do systematic reviews say?

31 questions · 31 findings · 13 reviews

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No studies found 8 · 25.8%GRADE not reported 1 · 3.2%Very low 10 · 32.3%Low 7 · 22.6%Moderate 2 · 6.5%High 3 · 9.7%

LABA/LAMA vs placebo

SGRQ Total SGRQ (Total) Score. Scale from: 0 to 100. Lower score indicates better quality of life. · Adults with COPD

1 finding from 1 review

Once daily long‐acting beta2‐agonists and long‐acting muscarinic antagonists in a combined inhaler versus placebo for… 2019 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 4952 participants
High

Ravulizumab vs placebo or alternative treatment

Health‐related quality of life · adults with aHUS

1 finding from 1 review

Interventions for atypical haemolytic uraemic syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
44 participants
Very low

Eculizumab vs placebo or alternative treatment

Health‐related quality of life · children and adults with aHUS

1 finding from 1 review

Interventions for atypical haemolytic uraemic syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
100 participants
Very low

GLP‐1 agonists vs placebo

Health‐related quality of life · adults with Parkinson's disease

1 finding from 1 review

GLP‐1 receptor agonists for Parkinson's disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Low

Potassium binder vs placebo

Health‐related quality of life · people with CKD (including haemodialysis)

1 finding from 1 review

Potassium binders for chronic hyperkalaemia in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 289 participants
Very low

Clindamycin phosphate 1.2% + tretinoin 0.025% gel vs placebo

HRQOL RosaQoL · Participants with rosacea

1 finding from 1 review

Interventions for rosacea 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 83 participants
Moderate

Metronidazole vs placebo

HRQOL ‐ not measured · Participants with rosacea

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for rosacea 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Tetracycline vs placebo

HRQOL ‐ not measured · Participants with rosacea

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for rosacea 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Doxycycline 40 mg vs placebo

HRQOL ‐ not measured · Participants with rosacea

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for rosacea 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Azelaic acid vs placebo

HRQOL ‐ not measured · Participants with rosacea

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for rosacea 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical ivermectin vs placebo

HRQOL DLQI and RosaQoL · Participants with rosacea

1 finding from 1 review

Interventions for rosacea 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 1371 participants
High

Light vibrational forces (LVF) vs Conventional orthodontic appliance treatment

Oral health-related quality of life · Adolescents and adults with malocclusion undergoing orthodontic treatment with fixed or removable appliances

1 finding from 1 review

Non‐surgical adjunctive interventions for accelerating tooth movement in patients undergoing orthodontic treatment 2023 · Cochrane All outcomes
Katchooi 2018 (unclear risk of bias): light vibrational forces had no statistically significant (P>0.05) effect on OHRQoL when used with orthodontic aligners.
1 study · 27 participants
GRADE not reported

Probiotics vs placebo

HRQoL (PedsQLTM 4.0 SF 15 (Scale from: 0 to 100)) · children and adults with CF

1 finding from 1 review

Probiotics for people with cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 37 participants
Low

Vitamin D vs placebo

HRQoL score (physical functioning) (change from baseline) · people with sickle cell disease

1 finding from 1 review

Vitamin D supplementation for sickle cell disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 37 participants
Low

Aerobic exercise vs no exercise or placebo exercise

Mean change in quality of life at ≥ 12 months using the 36‐Item Short Form Health Survey mental component score (SF‐36 MCS) · adults undergoing maintenance dialysis

1 finding from 1 review

Exercise training for adults undergoing maintenance dialysis 2022 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 306 participants
Very low

Resistance training vs no exercise or placebo exercise

Mean change in quality of life at ≥ 12 months using the 36‐Item Short Form Health Survey mental component score (SF‐36 MCS) · adults undergoing maintenance dialysis

1 finding from 1 review

Exercise training for adults undergoing maintenance dialysis 2022 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 176 participants
Very low

Aerobic exercise and strength training vs no exercise or placebo exercise

Mean change in quality of life at ≥ 12 months using the 36‐Item Short Form Health Survey mental component score (SF‐36 MCS) · adults undergoing maintenance dialysis

1 finding from 1 review

Exercise training for adults undergoing maintenance dialysis 2022 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 228 participants
Very low

Exercise vs no exercise or placebo exercise

Mean change in quality of life at ≥ 12 months using the 36‐Item Short Form Health Survey mental component score (SF‐36 MCS) · adults undergoing maintenance dialysis

1 finding from 1 review

Exercise training for adults undergoing maintenance dialysis 2022 · Cochrane Headline outcomes only
no estimate extracted
17 studies · 656 participants
Very low

Intravenous magnesium sulphate vs placebo

HRQoL score (Child‐reported PedsQL generic scale) at 1 week · people with sickle cell disease

1 finding from 1 review

Magnesium for treating sickle cell disease 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 202 participants
Low

Aerobic exercise vs no exercise or placebo exercise

Quality of Life: SF‐36 (physical component) · adults undergoing maintenance dialysis

1 finding from 1 review

Exercise training for adults undergoing maintenance dialysis 2022 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 306 participants
Very low