Cochrane · systematic review · CD014653
Exercise training for adults undergoing maintenance dialysis
Bernier-Jean, A, Beruni, NA, Bondonno, NP, et al. · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library
Kidney and TransplantAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
32
current version
GRADE rated
25
No studies
7
Included studies
NR
No studies 7 · 21.9%Ungraded 0 · 0%Very low 16 · 50%Low 4 · 12.5%Moderate 5 · 15.6%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Any exercise versus no exercise or placebo exercise for adults undergoing maintenance dialysis
Population: adults undergoing maintenance dialysis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death (any cause Any exercise vs no exercise or placebo exercise | RR 0.95 [0.56, 1.62] | 1 study · 296 participants | Very low Downgraded: risk of bias |
Cardiovascularevents Any exercise vs no exercise or placebo exercise | no estimate extracted | NR | No studies |
Fatigue Any exercise vs no exercise or placebo exercise | no estimate extracted | 6 studies · 326 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
HRQoL: Physical component scoreAssessed: SF‐36Scale: 0 to 100 Any exercise vs no exercise or placebo exercise | no estimate extracted | 17 studies · 656 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
HRQoL: Mental component scoreAssessed: SF‐36Scale: 0 to 100 Any exercise vs no exercise or placebo exercise | no estimate extracted | 17 studies · 656 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
PainAssessed: SF‐36Scale: 0 to 100 Any exercise vs no exercise or placebo exercise | no estimate extracted | 15 studies · 872 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
DepressionAssessed: multiple severity of depressive symptoms scales Any exercise vs no exercise or placebo exercise | no estimate extracted | 11 studies · 490 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Functional capacityAssessed: 6MWT Any exercise vs no exercise or placebo exercise | no estimate extracted | 19 studies · 827 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Aerobic exercise versus no exercise or placebo exercise for adults undergoing maintenance dialysis
Population: adults undergoing maintenance dialysis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death (any cause) Aerobic exercise vs no exercise or placebo exercise | RR 0.95 [0.56, 1.62] | 1 study · 296 participants | Very low Downgraded: risk of bias |
Cardiovascularevents Aerobic exercise vs no exercise or placebo exercise | no estimate extracted | NR | No studies |
Fatigue Aerobic exercise vs no exercise or placebo exercise | no estimate extracted | 4 studies · 221 participants | Very low Downgraded: risk of bias |
HRQoL: Physical component scoreAssessed: SF‐36Scale: 0 to 100 Aerobic exercise vs no exercise or placebo exercise | no estimate extracted | 9 studies · 306 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
HRQoL: Mental component scoreAssessed: SF‐36Scale: 0 to 100 Aerobic exercise vs no exercise or placebo exercise | no estimate extracted | 9 studies · 306 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
PainAssessed: SF‐36Scale: 0 to 100 Aerobic exercise vs no exercise or placebo exercise | no estimate extracted | 8 studies · 570 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
DepressionAssessed: multiple severity of depressive symptoms scales Aerobic exercise vs no exercise or placebo exercise | no estimate extracted | 4 studies · 127 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Functional capacityAssessed: 6MWT Aerobic exercise vs no exercise or placebo exercise | no estimate extracted | 10 studies · 515 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Resistance exercise versus no exercise or placebo exercise for adults undergoing maintenance dialysis
Population: adults undergoing maintenance dialysis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death (any cause) Resistance exercise vs no exercise or placebo exercise | no estimate extracted | NR | No studies |
Cardiovascular events Resistance exercise vs no exercise or placebo exercise | no estimate extracted | NR | No studies |
Fatigue Assessed: Profile of Mood States score Resistance exercise vs no exercise or placebo exercise | no estimate extracted | 1 study · 68 participants | Very low Downgraded: imprecision |
HRQoL: Physical component scoreAssessed: SF‐36Scale: 0 to 100 Resistance exercise vs no exercise or placebo exercise | no estimate extracted | 5 studies · 176 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
HRQoL: Mental component scoreAssessed: SF‐36Scale: 0 to 100 Resistance exercise vs no exercise or placebo exercise | no estimate extracted | 5 studies · 176 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
PainAssessed: SF‐36Scale: 0 to 100 Resistance exercise vs no exercise or placebo exercise | no estimate extracted | 5 studies · 154 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
DepressionAssessed: multiple severity of depressive symptoms scales Resistance exercise vs no exercise or placebo exercise | no estimate extracted | 2 studies · 99 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Functional capacityAssessed: 6MWT Resistance exercise vs no exercise or placebo exercise | no estimate extracted | 7 studies · 216 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Combined aerobic and resistance exercise versus no exercise or placebo exercise for adults undergoing maintenance dialysis
Population: adults undergoing maintenance dialysis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death (any cause) Combined aerobic and resistance exercise vs no exercise or placebo exercise | no estimate extracted | NR | No studies |
Cardiovascular events Combined aerobic and resistance exercise vs no exercise or placebo exercise | no estimate extracted | NR | No studies |
Fatigue Combined aerobic and resistance exercise vs no exercise or placebo exercise | no estimate extracted | NR | No studies |
HRQoL: Physical component scoreAssessed: SF‐36Scale: 0 to 100 Combined aerobic and resistance exercise vs no exercise or placebo exercise | no estimate extracted | 6 studies · 228 participants | Very low Downgraded: indirectness |
HRQoL: Mental component scoreAssessed: SF‐36Scale: 0 to 100 Combined aerobic and resistance exercise vs no exercise or placebo exercise | no estimate extracted | 6 studies · 228 participants | Very low Downgraded: indirectness |
PainAssessed: SF‐36Scale: 0 to 100 Combined aerobic and resistance exercise vs no exercise or placebo exercise | no estimate extracted | 3 studies · 161 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
DepressionAssessed: multiple severity of depressive symptoms scales Combined aerobic and resistance exercise vs no exercise or placebo exercise | no estimate extracted | 4 studies · 214 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Functional capacityAssessed: 6MWT Combined aerobic and resistance exercise vs no exercise or placebo exercise | no estimate extracted | 6 studies · 138 participants | Moderate Downgraded: indirectness |