Findings

What do systematic reviews say?

247 questions · 259 findings · 100 reviews

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No studies found 51 · 19.7%GRADE not reported 26 · 10%Very low 92 · 35.5%Low 59 · 22.8%Moderate 29 · 11.2%High 2 · 0.8%

Adverse event outcomes for dietary combined with physical activity interventions vs control

Depression · children aged 13‐18 years

1 finding from 1 review

Interventions for preventing obesity in children 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 779 participants
High

Psychological interventions vs usual care

Change in depression score ( · adolescents and adults with congenital heart disease

2 findings from 1 review

Psychological interventions for depression in adolescent and adult congenital heart disease 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 156 participants
Low
Psychological interventions for depression in adolescent and adult congenital heart disease 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 287 participants
Low

Pharmacological intervention and a form of psychotherapy (combination) vs pharmacological intervention and usual care or attention control (single)

Depression: meeting study criteria for depression at end of · people with depression after stroke

2 findings from 1 review

Pharmacological, non‐invasive brain stimulation and psychological interventions, and their combination, for treating… 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported
Pharmacological, non‐invasive brain stimulation and psychological interventions, and their combination, for treating… 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Pharmacological intervention and a form of psychotherapy (combination) vs pharmacological intervention and usual care or attention control (single)

Depression: mean scores at end of treatment (secondary outcome) · people with depression after stroke

1 finding from 1 review

Pharmacological, non‐invasive brain stimulation and psychological interventions, and their combination, for treating… 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 278 participants
Very low

Psychosocial interventions vs control

Depression at endpoint · adults (aged 18 and older) exposed to a traumatic event

1 finding from 1 review

Psychological and social interventions for the prevention of mental disorders in people living in low‐ and… 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 258 participants
Very low

Non‐invasive brain stimulation and pharmacological intervention (combination) vs a pharmacological intervention and sham stimulation or usual care (single)

Depression: meeting study criteria for depression at end of · people with depression after stroke

Pharmacological intervention and non‐invasive brain stimulation… may leads to lower depression: meeting the criteria for depression at end of treatment… compared with a pharmacological intervention and sham stimulation or usual care… (low certainty).

2 findings from 1 review

Pharmacological, non‐invasive brain stimulation and psychological interventions, and their combination, for treating… 2023 · Cochrane Headline outcomes only
RR 0.77 [0.64, 0.91]
3 studies · 392 participants
Low
Pharmacological, non‐invasive brain stimulation and psychological interventions, and their combination, for treating… 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Pharmacological intervention and a form of psychotherapy (combination) vs pharmacological intervention and usual care or attention control (single)

Depression: < 50% reduction in scale scores at end of treatment (primary outcome) · people with depression after stroke

1 finding from 1 review

Pharmacological, non‐invasive brain stimulation and psychological interventions, and their combination, for treating… 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Psychosocial interventions vs control

Depression at endpoint · children and adolescents exposed to traumatic events;

1 finding from 1 review

Psychological and social interventions for the prevention of mental disorders in people living in low‐ and… 2020 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 746 participants
Very low

Non‐invasive brain stimulation and pharmacological intervention (combination) vs a pharmacological intervention and sham stimulation or usual care (single)

Depression: mean scores at end of treatment (secondary outcome) · people with depression after stroke

1 finding from 1 review

Pharmacological, non‐invasive brain stimulation and psychological interventions, and their combination, for treating… 2023 · Cochrane Headline outcomes only
no estimate extracted
12 studies · 1055 participants
Very low

Workplace interventions vs usual care

Depression (6 months or more) MADRS measured 6 months after intervention (Aljumah 2015). PHQ‐9 measured 6 months after intervention (LeBlanc 2015). QIDS‐J measured 6 months after intervention (Aoki 2019a). Hospital Anxiety and Depression Scale (HA... · workers on sick leave

1 finding from 1 review

Workplace interventions to prevent work disability in workers on sick leave 2015 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 133 participants
Very low

Non‐invasive brain stimulation and pharmacological intervention (combination) vs a pharmacological intervention and sham stimulation or usual care (single)

Depression: < 50% reduction in scale scores at end of treatment (primary outcome) · people with depression after stroke

It is very uncertain whether pharmacological intervention and non‐invasive brain stimulation… changes depression: < 50% reduction in scale scores at end of treatment… compared with a pharmacological intervention and sham stimulation or usual care… (very low certainty).

1 finding from 1 review

Pharmacological, non‐invasive brain stimulation and psychological interventions, and their combination, for treating… 2023 · Cochrane Headline outcomes only
RR 0.95 [0.69, 1.3]
3 studies · 392 participants
Very low

Information or education intervention as part of a complex intervention vs complex intervention without information or education

Depression (lower scores mean less depression) · adult ICU patients and their carers

1 finding from 1 review

Information or education interventions for adult intensive care unit (ICU) patients and their carers 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 38 participants
Very low

Adverse event outcomes for dietary combined with physical activity interventions vs standard‐of‐care therapy

Postnatal depression · pregnant women, excluding women already diagnosed with GDM in this pregnancy and those with pre‐existing diabetes mellitus

1 finding from 1 review

Combined diet and exercise interventions for preventing gestational diabetes mellitus 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Self‐management interventions vs usual care

Anxiety and depression · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Self‐management interventions for people with chronic obstructive pulmonary disease 2022 · Cochrane Headline outcomes only
no estimate extracted
1647 participants
Moderate

Pharmaceutical interventions vs placebo

Depression: Mean scores at end of treatment · emotionalism after stroke

1 finding from 1 review

Pharmaceutical interventions for emotionalism after stroke 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 72 participants
Very low

Psychosocial interventions vs control

Proportion of individuals with a diagnosis of: PTSD, anxiety, depression, and somatic symptom and related disorders · children and adolescents exposed to traumatic events;

The review found no eligible studies for this question.

1 finding from 1 review

Psychological and social interventions for the prevention of mental disorders in people living in low‐ and… 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Psychosocial interventions vs control

Proportion of individuals with a diagnosis of: PTSD, anxiety, depression, and somatic symptom and related disorders · adults (aged 18 and older) exposed to a traumatic event

The review found no eligible studies for this question.

1 finding from 1 review

Psychological and social interventions for the prevention of mental disorders in people living in low‐ and… 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Pharmacological interventions vs placebo

Depression: meeting study criteria for depression at end of · people with depression after stroke

It is very uncertain whether pharmacological interventions changes depression: meeting study criteria for depression at end of… compared with placebo (very low certainty).

2 findings from 1 review

Pharmacological, non‐invasive brain stimulation and psychological interventions, and their combination, for treating… 2023 · Cochrane Headline outcomes only
RR 0.7 [0.55, 0.88]
8 studies · 1025 participants
Very low
Pharmacological, non‐invasive brain stimulation and psychological interventions, and their combination, for treating… 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

CBT interventions (CBT with and without exercise) vs control (standard care or sham treatments)

Depression · older adults (mean age minus 1 standard deviation is more than 60 years)

1 finding from 1 review

Cognitive behavioural therapy (CBT) with and without exercise to reduce fear of falling in older people living in the… 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 314 participants
Low

Pharmacological interventions vs placebo

Depression: mean scores at end of treatment (secondary outcome) · people with depression after stroke

1 finding from 1 review

Pharmacological, non‐invasive brain stimulation and psychological interventions, and their combination, for treating… 2023 · Cochrane Headline outcomes only
no estimate extracted
15 studies · 1535 participants
GRADE not reported