Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

87 questions · 117 findings · 22 reviews

No studies found 0 · 0%GRADE not reported 101 · 86.3%Very low 11 · 9.4%Low 2 · 1.7%Moderate 3 · 2.6%High 0 · 0%

Intervention not reported

Dental caries prevalence in permanent teeth (cavitated lesions) · Children aged 11-13 years in Latin America and the Caribbean

In other Latin American/Caribbean countries, pooled permanent-teeth caries prevalence was 64% (95% CI 45-79%), not significantly different from Brazil (p=0.42); certainty not graded.

1 finding from 1 review

Intervention not reported

Dental caries prevalence in permanent teeth (cavitated lesions) · Children aged 11-13 years in Latin America and the Caribbean

In Brazil, pooled permanent-teeth caries prevalence in 11-13 year-olds was 56% (95% CI 53-60%), with a significant declining trend over time; certainty not graded.

1 finding from 1 review

Intervention not reported

Dental caries prevalence in permanent teeth (cavitated lesions) · Children aged 11-13 years in Latin America and the Caribbean

About 58% of 11-13 year-old children in Latin America and the Caribbean had dental caries in permanent teeth (95% CI 54-61%); certainty not graded.

1 finding from 1 review

Disability (developmental, intellectual, or sensory) vs Persons without disabilities

Dental caries prevalence and severity · Persons with disabilities (children and adults with autism, Down syndrome, cerebral palsy, hearing impairment, or multiple disabilities)…

Dental caries prevalence and severity are high among persons with disabilities in Saudi Arabia (60% to over 80%), and the one comparative autism study reported significantly higher caries than controls; synthesized narratively (ungraded).

1 finding from 1 review

High-frequency sugar consumption (three or more times daily) vs Low sugar intake (fewer than three times daily)

Dental caries prevalence · Nigerian individuals, including children and adults, with primary or permanent dentition

High-frequency sugar consumption was associated with 18% higher but non-significant odds of dental caries in Nigeria (OR 1.18, 95% CI 0.87 to 1.59; I2=36%; ungraded).

1 finding from 1 review

Combined antiretroviral therapy (cART) vs Monotherapy or dual antiretroviral therapy

Dental caries prevalence and severity · Children and adolescents (<18 years) living with HIV (CLWH)

No significant difference in dental caries/severity between ART regimens (very low certainty).

1 finding from 1 review

Traditional screening (referral card given if the inspecting dentist judges the child needs to see a dentist) vs No screening

Dental caries prevalence · School children (aged 4 to 15 years), primary and secondary schools in the UK and India
1 finding from 1 review
  • Milsom 2006 measured prevalence of dental caries as mean number of teeth with active caries in primary teeth (dt) and permanent teeth (DT); post-intervention changes from baseline were not significant, and the authors…
    1 study · 16684 participants
    GRADE not reported

Clinical examination with risk-based recall vs Clinical examination with 6-month recall

Dental caries: prevalence of root caries · Dentate adults (aged 18 years and older) receiving dental check-ups in UK general dental practices (regular attenders)

Clinical examination with risk-based recall showed no clear difference in dental caries: prevalence of root caries compared with clinical examination with 6-month recall; GRADE not reported.

1 finding from 1 review

Clinical examination with risk-based recall vs Clinical examination with 24-month recall

Dental caries: prevalence of root caries · Dentate adults (aged 18 years and older) receiving dental check-ups in UK general dental practices (regular attenders)

Clinical examination with risk-based recall showed no clear difference in dental caries: prevalence of root caries compared with clinical examination with 24-month recall; GRADE not reported.

1 finding from 1 review

Clinical examination with 24-month recall vs Clinical examination with 6-month recall

Dental caries: prevalence of root caries · Dentate adults (aged 18 years and older) receiving dental check-ups in UK general dental practices (regular attenders)

Clinical examination with 24-month recall showed no clear difference in dental caries: prevalence of root caries compared with clinical examination with 6-month recall; GRADE not reported.

1 finding from 1 review

Overweight/obesity (combined) vs Normal Weight or Non‐Obese

Dental caries prevalence · Brazilian children/adolescents in permanent dentition (BMI classified by CDC 2000 growth charts)

The evidence is very uncertain about the effect of overweight/obesity on caries odds in the permanent dentition (very low certainty).

1 finding from 1 review

Overweight/obesity (combined) vs Normal Weight or Non‐Obese

Dental caries prevalence · Brazilian children/adolescents in permanent dentition (BMI classified by WHO 2006 Z-score)

A meta-analysis of 2 studies (permanent dentition, WHO 2006 Z-score) was rated very low certainty; the pooled effect was not shown in the article.

1 finding from 1 review

Obesity (Unclassified) vs Normal Weight or Non‐Obese

Dental caries prevalence · Brazilian children/adolescents in permanent dentition (BMI classified by CDC 2000 growth charts)

Normal-weight adolescents in the permanent dentition probably have greater odds of dental caries than obese peers (OR 2.53; moderate certainty).

1 finding from 1 review

Overweight/obesity (combined) vs Normal Weight or Non‐Obese

Dental caries prevalence · Brazilian children under 5 years in primary dentition (BMI classified by WHO 2006 Z-score)

The evidence is very uncertain about the effect of overweight/obesity on caries odds in the primary dentition (WHO 2006 Z-score; very low certainty).

1 finding from 1 review

Obesity (Unclassified) vs Normal Weight or Non‐Obese

Dental caries prevalence · Brazilian children in primary dentition (BMI classified by CDC 2000 growth charts)

The evidence is very uncertain about the effect of obesity on caries odds in the primary dentition (very low certainty).

1 finding from 1 review

Overweight/obesity (combined) vs Normal Weight or Non‐Obese

Dental caries prevalence · Brazilian children/adolescents (BMI classified by WHO 2007 percentile)

The evidence is very uncertain about the effect of overweight/obesity on caries odds (WHO 2007 percentile; very low certainty).

1 finding from 1 review

Overweight/obesity (combined) vs Normal Weight or Non‐Obese

Dental caries prevalence · Brazilian children in primary dentition (BMI classified by CDC 2000 growth charts)

The evidence is very uncertain about the effect of overweight/obesity on caries odds in the primary dentition (very low certainty).

1 finding from 1 review