Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

189 questions · 190 findings · 58 reviews

No studies found 43 · 22.6%GRADE not reported 14 · 7.4%Very low 53 · 27.9%Low 44 · 23.2%Moderate 27 · 14.2%High 9 · 4.7%

Acetaminophen plus Diphenhydramine vs placebo

Death ‐ not reported · patients with requirement of prophylaxis to avoid allergic and febrile non‐haemolytic transfusion reactions

Acetaminophen plus Diphenhydramine led to lower death ‐ not reported compared with placebo; GRADE not reported.

1 finding from 1 review

Acetaminophen plus Diphenhydrammine vs placebo (Unit of randomisation: transfusion)

Death ‐ not reported · patients with requirement of prophylaxis to avoid allergic and febrile non‐haemolytic transfusion reactions

Acetaminophen plus Diphenhydrammine led to lower death ‐ not reported compared with placebo (Unit of randomisation: transfusion); GRADE not reported.

1 finding from 1 review

Intervention not reported

Death from all causes · HIV‐negative people with tuberculous pericarditis

The intervention showed no clear difference in death from all causes (low certainty).

1 finding from 1 review

Intervention not reported

Death from all causes · HIV‐positive people with tuberculous pericarditis. Most patients (80%) not on antiretroviral drugs

It is very uncertain whether the intervention changes death from all causes (very low certainty).

1 finding from 1 review

Psychological intervention with or without other rehabilitation vs control (usual care/other rehabilitation)

Total mortalityDeaths · patients with coronary heart disease

Psychological intervention with or without other rehabilitation showed no clear difference in total mortalityDeaths compared with control (usual care/other rehabilitation) (moderate certainty).

1 finding from 1 review