Cochrane · systematic review · CD000526
Interventions for treating tuberculous pericarditis
Wiysonge, CS, Ntsekhe, M, Thabane, L, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library
Infectious DiseasesAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
10
current version
GRADE rated
10
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 5 · 50%Low 4 · 40%Moderate 1 · 10%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Corticosteroids for tuberculous pericarditis in HIV‐negative people
Population: HIV‐negative people with tuberculous pericarditis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death from all causes | RR 0.8 [0.59, 1.09] | 4 studies · 660 participants | Low Downgraded: risk of bias, imprecision |
Death from pericarditis | RR 0.39 [0.19, 0.8] | 4 studies · 660 participants | Moderate Downgraded: risk of bias |
Constrictive pericarditis | RR 0.72 [0.34, 1.55] | 2 studies · 281 participants | Very low Downgraded: risk of bias, imprecision |
Repeat pericardiocentesis | RR 0.85 [0.7, 1.04] | 2 studies · 492 participants | Low Downgraded: risk of bias, imprecision |
Cancer | RR 0.85 [0.05, 13.8] | 1 study · 256 participants | Very low Downgraded: risk of bias, imprecision |
Corticosteroids for tuberculous pericarditis in HIV‐positive people
Population: HIV‐positive people with tuberculous pericarditis. Most patients (80%) not on antiretroviral drugs
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death from all causes | RR 0.91 [0.34, 2.42] | 3 studies · 575 participants | Very low Downgraded: imprecision, inconsistency |
Death from pericarditis | RR 1.07 [0.46, 2.54] | 2 studies · 517 participants | Very low Downgraded: risk of bias, imprecision |
Constrictive pericarditis | RR 0.55 [0.26, 1.16] | 3 studies · 575 participants | Low Downgraded: imprecision |
Repeat pericardiocentesis | RR 1.02 [0.89, 1.18] | 2 studies · 517 participants | Low Downgraded: risk of bias, imprecision |
Cancer | RR 1.62 [0.27, 9.77] | 1 study · 502 participants | Very low Downgraded: risk of bias, imprecision |