Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

14 questions · 14 findings · 8 reviews

No studies found 4 · 28.6%GRADE not reported 2 · 14.3%Very low 0 · 0%Low 4 · 28.6%Moderate 4 · 28.6%High 0 · 0%

Aspirin vs placebo

Cardiovascular mortality · adults with hypertension (patients with atrial fibrillation, congestive heart failure, pre‐eclampsia or pulmonary hypertension were…

Aspirin showed no clear difference in cardiovascular mortality compared with placebo (low certainty).

1 finding from 1 review

Higher circulating 25-hydroxyvitamin D (25(OH)D) concentration vs Lower circulating 25-hydroxyvitamin D (25(OH)D) concentration

Cardiovascular mortality · Adults (general population)

Meta-analysis of observational studies (higher vs lower 25(OH)D) for Cardiovascular disease mortality: RR 0.55 (95% CI 0.36 to 0.85), statistically significant. Umbrella review outcome-level evidence grade: No conclusion.

1 finding from 1 review

Summary of findings table ‐ Psychological interventions vs control

Cardiovascular mortality · health problem or population

Summary of findings table ‐ Psychological treatment showed no clear difference in cardiovascular mortality ‐ long‐term compared with control; GRADE not reported.

1 finding from 1 review

Summary of findings table ‐ LSSS intervention vs regular salt

Cardiovascular mortality · Adults (general population)

Summary of findings table ‐ LSSS intervention showed no clear difference in cardiovascular mortality (events per 100,000 person‐years) compared with regular salt (moderate certainty).

1 finding from 1 review