Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

33 questions · 35 findings · 16 reviews · Headline outcomes only

No studies found 6 · 17.1%GRADE not reported 1 · 2.9%Very low 14 · 40%Low 6 · 17.1%Moderate 2 · 5.7%High 6 · 17.1%

Short‐acting insulin analogues vs regular human insulin

All‐cause mortality

Short‐acting insulin analogues showed no clear difference in all‐cause mortality (N) compared with regular human insulin (moderate certainty).

2 findings from 2 reviews · compare the 2 reviews

Intervention not reported

All‐cause mortality at 10 days ‐ short‐term treatment · patients with acute myocardial infarction or stroke1

It is very uncertain whether the intervention changes all‐cause mortality at 10 days ‐ short‐term treatment (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Deep neuromuscular blockade (NMB) vs moderate NMB

All‐cause mortality short‐term · adults undergoing intra‐ and transperitoneal laparoscopic procedures

It is very uncertain whether summary of findings table ‐ Deep neuromuscular blockade (NMB) changes all‐cause mortality short‐term compared with moderate NMB (very low certainty).

1 finding from 1 review

Transradial vs transfemoral approach

Short‐term all‐cause mortality · people with coronary artery disease undergoing diagnostic coronary angiography and percutaneous coronary intervention

Transradial leads to lower short‐term all‐cause mortality compared with transfemoral approach (high certainty).

1 finding from 1 review

Summary of findings table ‐ Psychological interventions vs control

All‐cause mortality ‐ short‐term · health problem or population

It is very uncertain whether summary of findings table ‐ Psychological treatment changes all‐cause mortality ‐ short‐term compared with control (very low certainty).

1 finding from 1 review

Cells vs no cells

All‐cause mortality ‐ short‐term · Anyone diagnosed with AMI

Cells showed no clear difference in all‐cause mortality ‐ short‐term compared with no cells (moderate certainty).

1 finding from 1 review

Epinephrine vs norepinephrine‐dobutamine

All‐cause short‐term mortality: 28 days · adults with cardiogenic shock

It is very uncertain whether epinephrine changes all‐cause short‐term mortality: 28 days compared with norepinephrine‐dobutamine (very low certainty).

1 finding from 1 review

Pharmacological treatment vs pharmacological treatment 2

All‐cause mortality ‐ short term (end of treatment) · health problem or population

It is very uncertain whether summary of findings table ‐ Pharmacological treatment 1 changes all‐cause mortality ‐ short term (end of treatment) compared with pharmacological treatment 2 (very low certainty).

1 finding from 1 review

Levosimendan vs dobutamine

All‐cause short‐term mortality: range 15 to 31 days · people with cardiogenic shock or low cardiac output syndrome

Levosimendan showed no clear difference in all‐cause short‐term mortality: range 15 to 31 days compared with dobutamine (low certainty).

1 finding from 1 review