Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

45 questions · 47 findings · 30 reviews

No studies found 6 · 12.8%GRADE not reported 2 · 4.3%Very low 12 · 25.5%Low 16 · 34%Moderate 6 · 12.8%High 5 · 10.6%

clopidogrel plus aspirin vs aspirin

All‐cause mortality · people with coronary disease, ischaemic cerebrovascular disease, peripheral arterial disease or at high risk of atherothrombotic disease

clopidogrel plus aspirin showed no clear difference in all‐cause mortality compared with aspirin alone (low certainty).

1 finding from 1 review

Systematic screening vs no/opportunistic screening

All‐cause mortality · general population including those at moderate to high risk of CVD, mean age between 30 and 75

Systematic screening showed no clear difference in all‐cause mortality compared with no/opportunistic screening (low certainty).

1 finding from 1 review

Intervention not reported

All‐cause mortality Median · individuals without known diabetes mellitus but at high risk for the condition

The intervention showed no clear difference in all‐cause mortality Median (low certainty).

1 finding from 1 review

Intervention not reported

All‐cause mortality at day 28 · unvaccinated, non‐hospitalized people with mild symptomatic COVID‐19 (WHO scale 2 to 3) at high risk for progression to severe disease

The intervention may leads to lower all‐cause mortality at day 28 (low certainty).

1 finding from 1 review