Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

9 questions · 11 findings · 8 reviews · Heart

No studies found 3 · 27.3%GRADE not reported 0 · 0%Very low 1 · 9.1%Low 4 · 36.4%Moderate 3 · 27.3%High 0 · 0%

Usual care with ivabradine vs Placebo, no intervention or usual care (with or without placebo)

Rate of serious adverse events · adults (≥ 18 years of age) with a diagnosis of chronic heart failure with reduced ejection fraction (HFrEF)
2 findings from 1 review

Usual care with ivabradine vs Placebo, no intervention or usual care (with or without placebo)

Rate of serious adverse events · patients with chronic heart failure with preserved ejection fraction
2 findings from 1 review