It is very uncertain whether adults: higher dose/longer course changes all adverse events compared with lower dose/shorter course (very low certainty).
Children: higher dose/longer course showed no clear difference in all adverse events compared with lower dose/shorter course (moderate certainty).
It is very uncertain whether two doses of HPV vaccine with longer interval changes serious adverse events at up to 5‐year compared with two doses of HPV vaccine with shorter interval (very low certainty).
The review found no eligible studies for this question.
Combination of manual therapy, exercise, electrotherapy and oral NSAID may leads to higher adverse events Pain persisting longer than 2 hours after treatment… compared with oral NSAID (low certainty).