Cochrane · systematic review · CD006595
Clinical pathways for chronic cough in children
McCallum, GB, Bailey, EJ, Morris, PS, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
AirwaysAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 5 · 100%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison
Population: children with chronic cough of unknown origin lasting longer than 4 weeks
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Clinical failure—primary outcome (by intention‐to‐treat analysis) | OR 0.35 [0.21, 0.58] | 1 study · 272 participants | Moderate Downgraded: risk of bias, imprecision |
PC‐QOL mean score at 6 weeks PC‐QOL is a 27‐item questionnaire. Each question has a 7‐point score ranging from 1 (worst quality of life) to 7 (best quality of life). Scores for each item were added and the average taken | no estimate extracted | 1 study · 226 participants | Moderate Downgraded: risk of bias, imprecision |
Duration of cough post randomisation | no estimate extracted | 1 study · 226 participants | Moderate Downgraded: risk of bias, imprecision |
Proportion of adverse events experienced | no estimate extracted | NR | Moderate Downgraded: risk of bias, imprecision |
Proportions of participants experiencing adverse events or complications | no estimate extracted | NR | Moderate Downgraded: risk of bias, imprecision |