Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

12 questions · 12 findings · 6 reviews

No studies found 3 · 25%GRADE not reported 3 · 25%Very low 5 · 41.7%Low 1 · 8.3%Moderate 0 · 0%High 0 · 0%

Infiltration injection local anaesthetic vs no local anaesthetic wound infiltration

Serious adverse events · patients with people undergoing laparoscopic cholecystectomy.

It is very uncertain whether local anaesthetic wound infiltration changes serious adverse events compared with no local anaesthetic wound infiltration (very low certainty).

1 finding from 1 review

Summary of findings: ultrasound‐guided injection of corticosteroid and local anaesthetic (UG CS+LA) vs injection with corticosteroid and anaesthetic

Adverse events · Morton's neuroma

Summary of findings: ultrasound‐guided injection of corticosteroid… showed no clear difference in adverse events compared with non‐ultrasound‐guided injection of corticosteroid and local… (low certainty).

1 finding from 1 review

Summary of findings table ‐ Intraperitoneal local anaesthetic vs control

Serious adverse events · people undergoing laparoscopic cholecystectomy.

It is very uncertain whether summary of findings table ‐ Intraperitoneal local anaesthetic changes serious adverse events compared with control (very low certainty).

1 finding from 1 review

Preoperative ibuprofen vs placebo

Adverse events · Children and adolescents having orthodontic separator placement (without local anaesthetic)
1 finding from 1 review