Question · asked by 1 review

Preoperative paracetamol (acetaminophen) vs placebo: Adverse events

Population
Children and adolescents having dental treatment under local anaesthetic (restorative and extraction treatments)
Intervention
Preoperative paracetamol (acetaminophen)
Comparison
placebo
Outcome
Adverse events

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Preoperative paracetamol (acetaminophen) vs Placebo
Adverse events · Children and adolescents having dental treatment under local anaesthetic (restorative and extraction treatments)
Preoperative analgesics for additional pain relief in children and adolescents having dental treatment (2016) · Cochrane All outcomes
No adverse events were recorded in Primosch 1995. The other two studies did not mention adverse events.1 studyGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Preoperative analgesics for additional pain relief in children and adolescents having dental treatment
2016 · Cochrane All outcomes
2016-01Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.