Question · asked by 1 review
Preoperative paracetamol (acetaminophen) vs placebo: Adverse events
- Population
- Children and adolescents having dental treatment under local anaesthetic (restorative and extraction treatments)
- Intervention
- Preoperative paracetamol (acetaminophen)
- Comparison
- placebo
- Outcome
- Adverse events
What each review found
Current versions onlyNo studies found 0 · 0%GRADE not reported 2 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Preoperative paracetamol (acetaminophen) vs Placebo Adverse events · Children and adolescents having dental treatment under local anaesthetic (restorative and extraction treatments) Preoperative analgesics for additional pain relief in children and adolescents having dental treatment (2016) · Cochrane All outcomes | No adverse events were recorded in Primosch 1995. The other two studies did not mention adverse events. | 1 study | GRADE not reported |
Preoperative paracetamol (acetaminophen) vs Placebo Adverse events · Children and adolescents having dental treatment under local anaesthetic (restorative and extraction treatments) Preoperative analgesics for additional pain relief in children and adolescents having dental treatment (2012) · Cochrane All outcomesearlier version CD008392.PUB2, superseded | No adverse events were recorded in Primosch 1995. The other two studies did not mention adverse events. | 1 study | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Preoperative analgesics for additional pain relief in children and adolescents having dental treatment 2016 · Cochrane All outcomes | 2016-01 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.