Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

53 questions · 54 findings · 31 reviews · Headline outcomes only

No studies found 9 · 16.7%GRADE not reported 5 · 9.3%Very low 14 · 25.9%Low 17 · 31.5%Moderate 4 · 7.4%High 5 · 9.3%

IVIg vs placebo

Adverse events · adults with renal vasculitis

Intravenous immunoglobulin may leads to higher adverse events compared with placebo (low certainty).

1 finding from 1 review

Reslizumab intravenous (IV) vs placebo

Serious adverse events · people with asthma

Reslizumab intravenous (IV) showed no clear difference in serious adverse events compared with placebo (high certainty).

1 finding from 1 review