Non‐serious adverse events Timing of outcome assessment: end of treatment · patients with borderline personality disorder
It is very uncertain whether mood stabilisers changes non‐serious adverse events Timing of outcome assessment: end of… compared with placebo (very low certainty).
1 finding from 1 review
Intervention not reported
Serious adverse events (such as donor site morbidity, failure of graft including re‐rupture) at 2 years · Adults with acute anterior cruciate ligament (ACL) injuries (young, active individuals)
1 finding from 1 review
Adverse effects: at least one serious adverse event · adults with multiple sclerosis Interventions: immunosuppressive and immunomodulatory drugs Comparator: placebo Outcome: withdrawals due to…
Palliative care showed no clear difference in serious adverse events Assessed by: number of participants… compared with usual care (low certainty).
1 finding from 1 review
Minor participant‐reported adverse events not requiring withdrawal of the treatment: Mild abdominal pain. · pityriasis rosea
Azithromycin showed no clear difference in minor participant‐reported adverse events not requiring withdrawal… compared with placebo or vitamins (moderate certainty).
1 finding from 1 review
Adverse events ‐ hyperpigmentation ( · people with acne scars
It is very uncertain whether fractional laser changes investigator‐assessed adverse events (short‐term) Hyperpigmentation… compared with non‐fractional non‐ablative laser (very low certainty).
1 finding from 1 review
Adverse effects (central nervous system) · people with depression after stroke
Non‐invasive brain stimulation showed no clear difference in adverse events: all ‐ central nervous system events (e.g. confusion,… compared with sham non‐invasive brain stimulation and/or usual care (low certainty).
1 finding from 1 review
Number of participants experiencing muscle‐related adverse events: e.g. soreness, discomfort, cramps, pain · men with urinary incontinence following prostate surgery
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Number of participants experiencing muscle‐related adverse events: e.g. soreness, discomfort, cramps, pain · men with urinary incontinence following prostate surgery
It is very uncertain whether combinations of conservative treatments changes number of participants experiencing muscle‐related adverse events:… compared with no treatment, sham treatment or verbal/written instruction (very low certainty).
1 finding from 1 review
Number of participants experiencing muscle‐related adverse events: e.g. soreness, discomfort, cramps, pain · men with urinary incontinence following prostate surgery
1 finding from 1 review
Non‐serious adverse events Timing of outcome assessment: end of treatment · patients with borderline personality disorder
It is very uncertain whether antipsychotics changes non‐serious adverse events Timing of outcome assessment: end of… compared with placebo (very low certainty).
1 finding from 1 review
Adverse events: minor gastrointestinal symptoms · pityriasis rosea
Erythromycin showed no clear difference in minor participant‐reported adverse events not requiring withdrawal… compared with placebo (moderate certainty).
1 finding from 1 review
Adverse events experienced at short or long term ‐ Serious cardiovascular adverse events ‐ bradycardia 24 weeks' · infantile haemangiomas (strawberry birthmarks) of the skin
1 finding from 1 review
Adverse events: treatment failure (non response, serious infection, persistently elevated creatinine) at 6 months · idiopathic steroid‐resistant nephrotic syndrome in children
Calcineurin inhibitor probably leads to lower adverse events: treatment failure at 6 months (non response, serious… compared with IV cyclophosphamide (moderate certainty).
1 finding from 1 review
Adverse events: all ‐ other events ‐ not listed above (e.g. dysuria, neck pain, eye discomfort) (secondary outcome) · people with depression after stroke
Non‐invasive brain stimulation showed no clear difference in adverse events: all ‐ other events ‐ not listed above (e.g. dysuria,… compared with sham non‐invasive brain stimulation and/or usual care (low certainty).
1 finding from 1 review
Adverse events and periodontal/secondary outcomes (gingival bleeding, gingival bleeding index, visible plaque index) · Children and adults with non-cavitated proximal (interproximal) caries lesions in primary and/or permanent teeth (ages 3-45)
Only three trials reported secondary/adverse outcomes; no adverse events were attributed to microinvasive treatment and periodontal findings were mixed and not pooled (ungraded).
1 finding from 1 review
Microinvasive interventions in the management of proximal caries lesions in primary and permanent teeth- systematic… 2025 All outcomesBaseline and follow-up · Multiple countries (Brazil, Saudi Arabia, Netherlands, USA, Turkey, Switzerland, Germany, New Zealand, Chile, Thailand); dental clinic/community settings
Reported narratively by 3 trials (Arthur 2018, Sarti 2020, Jorge 2019). No adverse events were attributed to microinvasive treatment. Gingival bleeding index: no significant difference in Arthur 2018 and Jorge 2019 but…
3 studies
GRADE not reported
Adverse events (self‐harm) Assessed by: mean number of self‐harm days in past 2 months Timing of assessment: 2 months · adults with antisocial personality disorder
1 finding from 1 review
Number of participants with grade 3‐4 (severe or life‐threatening) treatment‐related adverse events at 1 year (raw data) · bullous pemphigoid
Doxycycline probably leads to lower number of participants with grade 3‐4 (severe or life‐threatening)… compared with prednisolone (moderate certainty).
1 finding from 1 review
Number of participants experiencing surface or skin‐related adverse events: e.g. skin reactions, bruising, hypersensitivity to gel · men with urinary incontinence following prostate surgery
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Number of participants experiencing surface or skin‐related adverse events: e.g. skin reactions, bruising, hypersensitivity to gel · men with urinary incontinence following prostate surgery
1 finding from 1 review
Number of participants experiencing surface or skin‐related adverse events: e.g. skin reactions, bruising, hypersensitivity to gel · men with urinary incontinence following prostate surgery
1 finding from 1 review