Paracetamol vs placebo
Paracetamol showed no clear difference in any adverse events Up to 12 weeks' compared with placebo (high certainty).
- RR 1.07 [0.86, 1.33]1 study · 1624 participantsHigh
Paracetamol showed no clear difference in any adverse events Up to 12 weeks' compared with placebo (high certainty).
Recombinant human factor VII activated showed no clear difference in adverse events (overall incidence) compared with placebo (high certainty).
Vedolizumab showed no clear difference in serious adverse events (6–10 weeks) compared with placebo (low certainty).
Summary of findings table ‐ Subcutaneous biologics (dupilumab) showed no clear difference in incidence of serious adverse events compared with placebo (low certainty).
Summary of findings table ‐ Oral small molecule inhibitors… showed no clear difference in incidence of serious adverse events compared with placebo (low certainty).
It is very uncertain whether summary of findings table ‐ Topical small molecule inhibitors… changes incidence of serious adverse events compared with placebo (very low certainty).
Bamlanivimab showed no clear difference in adverse events: all grade by week 8 compared with placebo (low certainty).
It is very uncertain whether immunosuppressive treatment changes adverse events: malignancy at final compared with placebo/no treatment/non‐immunosuppressive supportive treatment (very low certainty).
Urtoxazumab (3.0 mg/kg) showed no clear difference in adverse events ‐ treatment emergent compared with placebo (low certainty).
Urtoxazumab (1.0 mg/kg) showed no clear difference in adverse events ‐ treatment emergent compared with placebo (low certainty).
Vitamin E leads to higher adverse events: haemorrhagic stroke compared with placebo (high certainty).
Oral olesoxime probably leads to lower adverse events related to treatment compared with placebo (moderate certainty).
Oral phenylbutyrate probably leads to higher adverse events related to treatment compared with placebo (moderate certainty).
Subcutaneous somatotropin showed no clear difference in adverse events related to treatment compared with placebo (low certainty).