Cochrane · systematic review · CD012230
Paracetamol for low back pain
Saragiotto, BT, Machado, GC, Ferreira, ML, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
Back and NeckAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 1 · 16.7%High 5 · 83.3%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Paracetamol compared with placebo for acute low back pain
Population: People with acute low back pain
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain 1 week (immediate term) (NRS 0 to 100) Paracetamol vs placebo | no estimate extracted | 1 study · 1520 participants | High |
Pain 12 weeks (short term) (NRS 0 to 100) Paracetamol vs placebo | no estimate extracted | 1 study · 1526 participants | High |
Disability 1 week (immediate term) (RMDQ 0 to 24) Paracetamol vs placebo | no estimate extracted | 1 study · 1511 participants | High |
Disability 12 weeks (short term) (RMDQ 0 to 24) Paracetamol vs placebo | no estimate extracted | 1 study · 1522 participants | High |
Any adverse events Up to 12 weeks' Paracetamol vs placebo | RR 1.07 [0.86, 1.33] | 1 study · 1624 participants | High |
Serious adverse events Up to 12 weeks' Paracetamol vs placebo | RR 0.9 [0.3, 2.67] | 1 study · 1643 participants | Moderate Downgraded: imprecision |