Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,199 questions · 1,226 findings · 451 reviews

No studies found 289 · 23.6%GRADE not reported 121 · 9.9%Very low 350 · 28.5%Low 279 · 22.8%Moderate 139 · 11.3%High 48 · 3.9%

Prophylactic perindopril (2 mg to 4 mg daily) vs placebo

Adverse events · boys with DMD, normal cardiac examination and LVEF > 55% at baseline

Prophylactic perindopril (2 mg to 4 mg daily) showed no clear difference in adverse events compared with placebo (low certainty).

1 finding from 1 review

NPWT vs dressings

Adverse events · treating foot wounds in people with diabetes mellitus

The review found no eligible studies for this question.

2 findings from 1 review

Parent‐mediated communication intervention vs no intervention

Adverse events · children up to 5 years of age with a communication difficulty associated with any non‐progressive motor disorder acquired before 2 years…

The review found no eligible studies for this question.

1 finding from 1 review

Keratinocyte growth factor (KGF; palifermin or repifermin), intravenous vs placebo

Adverse events · Adults with cancer receiving treatment
1 finding from 1 review