Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

458 questions · 473 findings · 205 reviews

No studies found 128 · 27.1%GRADE not reported 49 · 10.4%Very low 142 · 30%Low 106 · 22.4%Moderate 36 · 7.6%High 12 · 2.5%

Higher BP target (< 150‐160/95‐105 mmHg) vs lower BP target (< 140/90 mmHg)

Serious adverse events: cardiovascular events · older adults with primary hypertension

Higher BP target (< 150‐160/95‐105 mmHg) showed no clear difference in cardiovascular serious adverse events compared with lower BP target (< 140/90 mmHg) (low certainty).

1 finding from 1 review

Primary‐level worker‐led collaborative care vs usual care

Adverse events ‐ death · adults with common mental disorders

It is very uncertain whether primary‐level worker‐led collaborative care changes adverse events ‐ death compared with usual care (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Deep neuromuscular blockade (NMB) vs shallow NMB

Short‐term serious adverse events (SAEs) · adults undergoing intra‐ and transperitoneal laparoscopic procedures

It is very uncertain whether summary of findings table ‐ Deep neuromuscular blockade (NMB) changes short‐term serious adverse events (SAEs) compared with shallow NMB (very low certainty).

1 finding from 1 review

Chlorhexidine varnish vs placebo or no treatment

Adverse events (e.g. ulcers, tooth staining) · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
1 finding from 1 review

Higher polyunsaturated fatty acid (PUFA) vs lower PUFA

Major adverse cardiac and cerebrovascular events · people with or without existing CVD, men and women

It is very uncertain whether higher polyunsaturated fatty acid (PUFA) changes major adverse cardiac and cerebrovascular events compared with lower PUFA (very low certainty).

1 finding from 1 review

Transmural care vs usual follow‐up

Adverse events: readmission to clinical rehabilitation · people with spinal cord injury receiving rehabilitation treatment for the first time

It is very uncertain whether transmural care changes adverse events: readmission to clinical rehabilitation compared with usual follow‐up care (very low certainty).

1 finding from 1 review