Cochrane · systematic review · CD011575
Blood pressure targets for hypertension in older adults
Garrison, SR, Kolber, MR, Korownyk, CS, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library
HypertensionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 4 · 100%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Higher BP target (< 150‐160/95‐105 mmHg) compared with lower BP target (< 140/90 mmHg) for cardiovascular risk reduction
Population: older adults with primary hypertension
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All‐cause mortality Higher BP target (< 150‐160/95‐105 mmHg) vs lower BP target (< 140/90 mmHg) | RR 1.24 [0.99, 1.54] | 3 studies · 8221 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Stroke Higher BP target (< 150‐160/95‐105 mmHg) vs lower BP target (< 140/90 mmHg) | RR 1.25 [0.94, 1.67] | 3 studies · 8221 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Cardiovascular serious adverse events Higher BP target (< 150‐160/95‐105 mmHg) vs lower BP target (< 140/90 mmHg) | RR 1.19 [0.98, 1.45] | 3 studies · 8221 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Withdrawals due to adverse effects Higher BP target (< 150‐160/95‐105 mmHg) vs lower BP target (< 140/90 mmHg) | RR 0.83 [0.58, 1.19] | 2 studies · 7497 participants | Low Downgraded: risk of bias, imprecision, inconsistency |