Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

319 questions · 326 findings · 94 reviews

No studies found 89 · 27.3%GRADE not reported 19 · 5.8%Very low 89 · 27.3%Low 81 · 24.8%Moderate 40 · 12.3%High 8 · 2.5%

Chemical peeling vs combined chemical peeling plus any active intervention

Participant‐assessed adverse events (short‐term) N of participants with adverse events · people with acne scars

It is very uncertain whether chemical peeling changes participant‐assessed adverse events (short‐term) N of participants… compared with combined chemical peeling plus any active intervention (very low certainty).

1 finding from 1 review

Fecal microbiota transplantation vs control

Any adverse events with use of FMT for induction of remission in UC (RR > 1 favors control) · people with active UC

Fecal microbiota transplantation showed no clear difference in any adverse events with use of FMT for induction of remission in UC… compared with control (low certainty).

1 finding from 1 review

Psychosocial interventions vs inactive control

Adverse events (a count of reported harms or adverse events/experiences over life of study/ · survivors of sexual violence and abuse

It is very uncertain whether summary of findings table ‐ Psychosocial interventions changes adverse events (a count of reported harms or adverse… compared with inactive control (very low certainty).

1 finding from 1 review

Fecal microbiota transplantation vs control

Serious adverse events with use of FMT for induction of remission in UC (RR > 1 favors control) · people with active UC

It is very uncertain whether fecal microbiota transplantation changes serious adverse events with use of FMT for induction of remission in… compared with control (very low certainty).

1 finding from 1 review

Bronchial thermoplasty vs active control

Participants admitted to hospital because of respiratory adverse events (post‐treatment period) · adults with asthma

Bronchial thermoplasty showed no clear difference in participants admitted to hospital because of respiratory adverse… compared with any active control (moderate certainty).

1 finding from 1 review

Patching vs active observation

Minor adverse events Defined as any adverse event within 8 weeks of surgery that does not require further intervention · people with intermittent exotropia, aged less than 11 years

The review found no eligible studies for this question.

1 finding from 1 review

PFMT added to drug therapy vs drug therapy alone

Number of women reporting adverse events ‐ not reported · women with urinary incontinence

It is very uncertain whether PFMT added to drug therapy changes number of women reporting adverse events compared with drug therapy alone (very low certainty).

1 finding from 1 review

tDCS vs active control

Dropouts, adverse events and deaths during intervention phase Numbers of dropouts, adverse events and deaths from all causes · people with stroke

tDCS showed no clear difference in secondary outcome measure: dropouts, adverse events and deaths… compared with any type of active control intervention (moderate certainty).

1 finding from 1 review

Conventional occlusion vs atropine penalization

Adverse events (reported occurrence of: mild reduction in the visual acuity of the sound eye not requiring treatment; light sensitivity; skin, lid, or conjunctival irritation) Assessed at different time points (17 weeks or 2 years). · Participants of any age with either unilateral strabismic, anisometropic, or mixed (strabismic‐refractive) amblyopia; deprivation…
1 finding from 1 review