Manual therapy, prescribed exercises or both vs placebo
Proportion with adverse events · lateral elbow pain
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Findings
What do systematic reviews say?
1,199 questions · 1,226 findings · 451 reviews
No studies found 289 · 23.6%GRADE not reported 121 · 9.9%Very low 350 · 28.5%Low 279 · 22.8%Moderate 139 · 11.3%High 48 · 3.9%
Prevention of UI after radical: PFMT ± biofeedback vs no treatment
Adverse events ‐ not reported · All men after radical prostatectomy
The review found no eligible studies for this question.
1 finding from 1 review
- Conservative management for postprostatectomy urinary incontinence 2015 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Preloading nicotine replacement therapy (NRT) vs standard‐use NRT
Overall serious adverse events · people who smoke
Preloading nicotine replacement therapy (NRT) showed no clear difference in overall serious adverse events compared with standard‐use NRT (low certainty).
1 finding from 1 review
- Different doses, durations and modes of delivery of nicotine replacement therapy for smoking cessation 2023 · Cochrane Headline outcomes onlyRR 1.11 [0.59, 2.09]4 studies · 3908 participantsLow
Antidepressants vs placebo
Non‐serious adverse events Timing of outcome assessment: end of treatment · patients with borderline personality disorder
The review found no eligible studies for this question.
1 finding from 1 review
- Pharmacological interventions for people with borderline personality disorder 2022 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Sclerotherapy plus compression vs sclerotherapy (any sclerosant)
Adverse events ‐ hyperpigmentation ( · people with telangiectasias and reticular veins
Sclerotherapy plus compression showed no clear difference in adverse events ‐ hyperpigmentation ( compared with sclerotherapy alone (moderate certainty).
1 finding from 1 review
- RR 0.93 [0.41, 2.07]2 studies · 196 participantsModerate
Prevention of UI after radical: combinations of treatments vs no treatment
Adverse events ‐ not reported · All men after radical prostatectomy
The review found no eligible studies for this question.
1 finding from 1 review
- Conservative management for postprostatectomy urinary incontinence 2015 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Prevention of UI after radical: electric or magnetic energy vs no treatment
Adverse events ‐ not reported · All men after radical prostatectomy
The review found no eligible studies for this question.
1 finding from 1 review
- Conservative management for postprostatectomy urinary incontinence 2015 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Prevention of UI after TURP: pre or post‐operative PFMT ± biofeedback vs no treatment
Adverse events ‐ not reported · All men after TURP
The review found no eligible studies for this question.
1 finding from 1 review
- Conservative management for postprostatectomy urinary incontinence 2015 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Antibiotics vs placebo or no treatment
All adverse events · children with previous UTI and most do not have a renal tract abnormality such as VUR
Antibiotic treatment showed no clear difference in all adverse events compared with placebo or no treatment (low certainty).
1 finding from 1 review
- Long‐term antibiotics for preventing recurrent urinary tract infection in children 2019 · Cochrane Headline outcomes onlyRR 2.31 [0.03, 170.67]2 studies · 914 participantsLow
Azithromycin vs doxycycline
Adverse events Men · men and non‐pregnant women with symptomatic (uterine cervicitis and urethritis), or asymptomatic genital CT infection, diagnosed by cell…
Azithromycin showed no clear difference in adverse events Men compared with doxycycline (low certainty).
1 finding from 1 review
- Antibiotics for treating urogenital Chlamydia trachomatis infection in men and non‐pregnant women 2019 · Cochrane Headline outcomes onlyRR 0.83 [0.67, 1.02]6 studies · 1424 participantsLow
Raloxifene vs placebo
Adverse events ‐ depression · women with endometriosis, following complete surgical excision of lesions
It is very uncertain whether raloxifene changes adverse events ‐ depression compared with placebo (very low certainty).
1 finding from 1 review
- Selective oestrogen receptor modulators (SERMs) for endometriosis 2021 · Cochrane Headline outcomes onlyRR 1.91 [0.62, 5.92]1 study · 93 participantsVery low
Summary of findings table ‐ Methylprednisolone vs dexamethasone
Serious adverse events ‐ not reported · hospitalised and unvaccinated individuals with a confirmed or suspected diagnosis of symptomatic COVID‐19
The review found no eligible studies for this question.
1 finding from 1 review
- Systemic corticosteroids for the treatment of COVID‐19: Equity‐related analyses and update on evidence 2022 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Elective radical (comprehensive) neck dissection vs Elective selective neck dissection
Adverse events associated with treatment · Adults with oral cavity cancer
1 finding from 1 review
- Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomesAdverse events (BHNCSG 1998): flap necrosis, wound infection, fistula, vascular rupture, haematoma, seroma, chyle fistula; no complications in 45/76 modified radical ND and 54/72 supraomohyoid ND; 2 vs 1 postoperative…1 study · 148 participantsLow
Clinical effect of simple decompression vs transposition
Wound infection · patients with ulnar neuropathy at the elbow
Simple decompression probably leads to lower adverse events: proportion of participants with deep/superficial… compared with transposition (moderate certainty).
1 finding from 1 review
- RR 0.32 [0.12, 0.85]3 studies · 261 participantsModerate
Summary of findings table ‐ Oral small molecule inhibitors (apremilast or baricitinib) vs placebo
Incidence of serious adverse events · adults with alopecia areata
Summary of findings table ‐ Oral small molecule inhibitors… showed no clear difference in incidence of serious adverse events compared with placebo (low certainty).
1 finding from 1 review
- RR 1.47 [0.6, 3.6]3 studies · 1224 participantsLow
Summary of findings table ‐ Oral classical immunosuppressants (prednisolone or cyclosporine) vs placebo
Incidence of serious adverse events · adults with alopecia areata
1 finding from 1 review
- no estimate extracted2 studies · 79 participantsVery low
Summary of findings table ‐ Intralesional classical immunosuppresants (betamethasone or triamcinolone) vs placebo
Incidence of serious adverse events · adults with alopecia areata
1 finding from 1 review
- no estimate extracted4 studies · 543 participantsVery low
Intervention not reported
Other adverse events · preventing and treating osteoporosis in postmenopausal women
1 finding from 1 review
- Exercise for preventing and treating osteoporosis in postmenopausal women 2011 · Cochrane Headline outcomes onlyno estimate extracted11 studies · 907 participantsGRADE not reported
Intrauterine infusion/injection of autologous platelet‐rich plasma vs placebo or no intervention
Adverse events: preterm delivery · women undergoing assisted reproduction
Intrauterine infusion/injection of autologous platelet‐rich plasma may leads to higher adverse events: preterm delivery compared with no intervention or placebo (low certainty).
1 finding from 1 review
- OR 8.02 [1.72, 37.33]1 study · 120 participantsLow
Oral immunosuppressants: oral cyclosporin vs topical betamethasone dipropionate
Number of participants with any adverse event (primary tolerability outcome) · people with hand eczema, continuously for 6 months, significant disability, inadequate response to conventional treatment, confirmation by…
Oral immunosuppressants: oral cyclosporin showed no clear difference in primary: adverse events ‐ at least 1 adverse event compared with topical betamethasone dipropionate (moderate certainty).
1 finding from 1 review
- RR 1.22 [0.8, 1.86]1 study · 55 participantsModerate