What do systematic reviews say?

Extra-oral pulp extirpation at day 0 vs Intra-oral pulp extirpation at day 7

• Interventions for treating traumatised permanent front teeth: avulsed (knocked out) and replanted 2019 · Cochrane All outcomes
  Giannetti 2006 did not report this outcome; following email correspondence, authors reported no adverse effects were seen (uncertain whether formally assessed).
  1 study
  GRADE not reported

Acute to Chronic MND: Scapulothoracic + UE Strengthening vs control

The review found no eligible studies for this question.

• Exercises for mechanical neck disorders 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Acute to Chronic MND: Scapulothoracic/UE Endurance Training vs control

Acute to Chronic MND: Scapulothoracic/UE Endurance Training led to lower adverse effects compared with CONTROL; GRADE not reported.

• Exercises for mechanical neck disorders 2015 · Cochrane Headline outcomes only
  no estimate extracted
  2 participants
  GRADE not reported

Chronic MND: Cervical/Scapulothoracic/UE Stretch + UE Endurance Training vs no treatment or waiting list

The review found no eligible studies for this question.

• Exercises for mechanical neck disorders 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Acute Radiculopathy: Cervical Stretch/ROM + Cervical/Scapulothoracic/UE Strengthening + Static/Dynamic Cervical Stabilization vs WAIT LIST

The review found no eligible studies for this question.

• Exercises for mechanical neck disorders 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Chronic MND: Cervical Stretch/ROM Exercises + Cervical/Scapulothoracic Strengthening + Static/Dynamic Cervical/Shoulder Stabilization vs WAIT LIST

The review found no eligible studies for this question.

• Exercises for mechanical neck disorders 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Chronic CGH: Cervical/Scapulothoracic Strengthening with Endurance Training + Craniocervical Pressure Biofeedback + Dynamic Cervical Stabilization vs no intervention

• Exercises for mechanical neck disorders 2015 · Cochrane Headline outcomes only
  no estimate extracted
  6 participants
  GRADE not reported

Chronic MND: Cervical/UE Stretch/ROM Exercises + Cervical/Scapulothoracic+/‐UE Strengthening + Dynamic/Static Cervical Stabilization + ANOTHER INTERVENTION vs THAT SAME INTERVENTION

• Exercises for mechanical neck disorders 2015 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 8 participants
  GRADE not reported

Chronic CGH: Cervical/Scapulothoracic Strengthening with Endurance Training + Craniocervical Pressure Biofeedback + Dynamic Cervical Stabilization + Manual Therapy vs manual therapy

• Exercises for mechanical neck disorders 2015 · Cochrane Headline outcomes only
  no estimate extracted
  6 participants
  GRADE not reported

Summary of findings table ‐ immunostimulant vs placebo

Summary of findings table ‐ immunostimulant showed no clear difference in adverse events/side effects compared with placebo (high certainty).

• Immunostimulants versus placebo for preventing exacerbations in adults with chronic bronchitis or chronic obstructive… 2022 · Cochrane Headline outcomes only
  OR 1.01 [0.84, 1.21]
  20 studies · 3780 participants
  High

Condiments/seasonings fortified with iron plus other micronutrients vs condiments/seasonings fortified with other micronutrients except iron

• Fortification of condiments and seasonings with iron for preventing anaemia and improving health 2023 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Condiments/seasonings fortified with iron vs unfortified condiments/seasonings

• Fortification of condiments and seasonings with iron for preventing anaemia and improving health 2023 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Resin-based fissure sealant (2nd/3rd/4th generation) vs No sealant (control/no treatment)

• Pit and fissure sealants for preventing dental decay in permanent teeth 2017 · Cochrane All outcomes
  Two trials measured adverse effects. None were reported.
  2 studies
  GRADE not reported

Glass ionomer-based sealant vs No sealant (control/no treatment)

The review found no eligible studies for this question.

• Pit and fissure sealants for preventing dental decay in permanent teeth 2017 · Cochrane All outcomes
  Adverse effects not measured.
  Studies not reported
  No studies found

Beta‐carotene vs placebo

• Antioxidant vitamin and mineral supplements for preventing age‐related macular degeneration 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  High

Vitamin C vs placebo

The review found no eligible studies for this question.

• Antioxidant vitamin and mineral supplements for preventing age‐related macular degeneration 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Multivitamin vs placebo

• Antioxidant vitamin and mineral supplements for preventing age‐related macular degeneration 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Moderate

Targeted mass media intervention vs general population mass media intervention

The review found no eligible studies for this question.

• Targeted mass media interventions promoting healthy behaviours to reduce risk of non‐communicable diseases in adult,… 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Glass ionomer-based sealant vs Resin-based sealant

• Pit and fissure sealants for preventing dental decay in permanent teeth 2017 · Cochrane All outcomes
  One trial measured adverse effects. None reported.
  1 study
  GRADE not reported

Sodium hypochlorite 1.3% with MTAD final rinse vs Sodium hypochlorite 1.3% with normal saline final rinse

The review found no eligible studies for this question.

• Irrigants for non‐surgical root canal treatment in mature permanent teeth 2012 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found