Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

6 questions · 6 findings · 3 reviews · Headline outcomes only

No studies found 2 · 33.3%GRADE not reported 3 · 50%Very low 1 · 16.7%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Primary outcome: topical local anaesthetics vs infiltrated local anaesthetics or other topical agents

Anaesthetic‐related adverse effects · adults and paediatric patients with dermal laceration

Primary outcome: topical local anaesthetics led to lower anaesthetic‐related adverse effects compared with infiltrated local anaesthetics or other topical agents; GRADE not reported.

1 finding from 1 review

Alginate dressing vs hydrocolloid dressing

Number of participants reporting an adverse event · people with venous leg ulcers

It is very uncertain whether alginate dressing changes proportion of participants experiencing adverse effects at 6 weeks compared with hydrocolloid dressing (very low certainty).

1 finding from 1 review