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Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

11 questions · 11 findings · 6 reviews · Headline outcomes only

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No studies found 2 · 18.2%GRADE not reported 3 · 27.3%Very low 3 · 27.3%Low 3 · 27.3%Moderate 0 · 0%High 0 · 0%

Antibiotic prophylaxis vs no treatment or placebo

Adverse effects of antibiotics (skin rash) · Women who had normal vaginal births

It is very uncertain whether routine antibiotic prophylaxis changes adverse effects of antibiotics (skin rash) compared with no treatment or placebo (very low certainty).

1 finding from 1 review

Antibiotics vs placebo

Total adverse effects · women having elective abdominal hysterectomy

It is very uncertain whether antibiotics changes total adverse effects compared with placebo (very low certainty).

1 finding from 1 review

Summary of findings ‐ withdrawal of penicillin prophylaxis vs continuation

Nausea and vomiting · children with SCD who have been receiving prophylactic penicillin for at least two years

Summary of findings ‐ withdrawal of penicillin prophylaxis showed no clear difference in adverse effects: incidences of nausea and vomiting compared with continuation (low certainty).

1 finding from 1 review

Intervention not reported

Total adverse effects · women having elective vaginal hysterectomy
1 finding from 1 review

Intervention not reported

Total adverse effects · women having elective abdominal hysterectomy

The review found no eligible studies for this question.

1 finding from 1 review