Cochrane · systematic review · CD007482
Antibiotic prophylaxis versus no prophylaxis for preventing infection after cesarean section
Smaill, FM, Grivell, RM · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
Pregnancy and ChildbirthAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 2 · 25%Very low 0 · 0%Low 1 · 12.5%Moderate 5 · 62.5%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Antibiotics versus no antibiotics for preventing infection after cesarean section
Population: Women undergoing cesarean section.
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Maternal wound infection Antibiotics vs no antibiotics | RR 0.4 [0.35, 0.46] | 82 studies · 14407 participants | Moderate Downgraded: risk of bias |
Maternal endometritis Antibiotics vs no antibiotics | RR 0.38 [0.34, 0.42] | 83 studies · 13548 participants | Moderate Downgraded: risk of bias |
Maternal serious infectious complications Antibiotics vs no antibiotics | RR 0.31 [0.2, 0.49] | 32 studies · 6159 participants | Moderate |
Adverse effects on infant Antibiotics vs no antibiotics | no estimate extracted | 0 studies · 0 participants | Ungraded |
Antibiotics versus no antibiotics for preventing infection after elective cesarean section
Population: Women undergoing elective cesarean section
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Maternal wound infection Antibiotics vs no antibiotics | RR 0.62 [0.47, 0.82] | 17 studies · 3537 participants | Moderate |
Maternal endometritis Antibiotics vs no antibiotics | RR 0.38 [0.24, 0.61] | 15 studies · 2502 participants | Moderate |
Maternal serious infectious complications Antibiotics vs no antibiotics | RR 1.01 [0.04, 24.21] | 4 studies · 545 participants | Low |
Adverse effects on infant Antibiotics vs no antibiotics | no estimate extracted | 0 studies · 0 participants | Ungraded |