Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

584 questions · 590 findings · 240 reviews

No studies found 106 · 18%GRADE not reported 94 · 15.9%Very low 137 · 23.2%Low 134 · 22.7%Moderate 98 · 16.6%High 21 · 3.6%

Antidepressants (trazodone 200 mg/day) vs placebo

Abdominal pain · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms

It is very uncertain whether antidepressants (trazodone 200 mg/day) changes adverse effects: abdominal pains compared with placebo (very low certainty).

1 finding from 1 review

Injectional collagenase vs placebo

Treatment‐related adverse effects · men with Peyronie's disease (diagnosis of disease: at least 12 months, penile curvature: at least 30 degrees)

The review found no eligible studies for this question.

2 findings from 1 review

Potassium paraaminobenzoate vs placebo

Treatment‐related adverse effects · men with acute (maximum of 12 months) Peyronie's disease with no prior treatment and no evidence of calcified plaques (pain during…

It is very uncertain whether potassium paraaminobenzoate changes treatment‐related adverse effects compared with placebo (very low certainty).

1 finding from 1 review

Pregabalin vs placebo

Treatment‐related adverse effects · adults and children with sickle cell disease experiencing neuropathic pain

It is very uncertain whether summary of findings ‐ Pharmacological intervention (pregabalin) changes treatment‐related adverse effects compared with placebo (very low certainty).

1 finding from 1 review

First‐line beta‐blocker vs placebo

Withdrawals due to adverse events · adults with primary hypertension

First‐line beta‐blocker may leads to higher withdrawal due to adverse effects compared with placebo (low certainty).

1 finding from 1 review

Betahistine vs placebo

Other adverse effects (yes or no) · patients with subjective idiopathic tinnitus
2 findings from 1 review

Roselle extract vs placebo

Withdrawals due to adverse events · hypertension in adults with type 2 diabetes mellitus

The review found no eligible studies for this question.

1 finding from 1 review