Findings

What do systematic reviews say?

4 questions · 4 findings · 4 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 50%Low 1 · 25%Moderate 1 · 25%High 0 · 0%

hCG vs placebo/no treatment

Clinical pregnancy · subfertile women

It is very uncertain whether hCG changes clinical pregnancy compared with placebo/no treatment (very low certainty).

1 finding from 1 review

Luteal phase support for assisted reproduction cycles 2015 · Cochrane Headline outcomes only
OR 1.3 [0.9, 1.88]
5 studies · 746 participants
Very low

RhCG vs uhCG

Clinical pregnancy rate · patients with final oocyte maturation triggering in IVF and ICSI cycles

RhCG showed no clear difference in clinical pregnancy rate per woman compared with uhCG (moderate certainty).

1 finding from 1 review

Recombinant versus urinary human chorionic gonadotrophin for final oocyte maturation triggering in IVF and ICSI cycles 2016 · Cochrane Headline outcomes only
OR 1.06 [0.87, 1.29]
13 studies · 1806 participants
Moderate

Low‐dose hCG vs FSH throughout the COH

Clinical pregnancy · women undergoing assisted reproduction

Low‐dose hCG showed no clear difference in clinical pregnancy compared with FSH throughout the COH (low certainty).

1 finding from 1 review

FSH replaced by low‐dose hCG in the late follicular phase versus continued FSH for assisted reproductive techniques 2013 · Cochrane Headline outcomes only
RR 1.19 [0.92, 1.55]
5 studies · 351 participants
Low

Human chorionic gonadotropin (hCG) injection vs no treatment

Clinical pregnancy rate · women trying to conceive by intrauterine insemination

It is very uncertain whether human chorionic gonadotropin (hCG) injection changes clinical pregnancy rate compared with no treatment (very low certainty).

1 finding from 1 review

Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse 2022 · Cochrane Headline outcomes only
RR 0.93 [0.4, 2.13]
1 study · 130 participants
Very low