Cochrane · systematic review · CD010042
FSH replaced by low‐dose hCG in the late follicular phase versus continued FSH for assisted reproductive techniques
Martins, WP, Vieira, ADD, Figueiredo, JBP, et al. · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library
Gynaecology and FertilityAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 3 · 42.9%Low 2 · 28.6%Moderate 2 · 28.6%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Low‐dose hCG compared to FSH throughout the COH for assisted reproductive techniques
Population: women undergoing assisted reproductive techniques
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Live birth Low‐dose hCG vs FSH throughout the COH | RR 1.56 [0.75, 3.25] | 2 studies · 130 participants | Very low Downgraded: risk of bias, imprecision |
OHSS Low‐dose hCG vs FSH throughout the COH | OR 0.3 [0.06, 1.59] | 5 studies · 351 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Ongoing pregnancy Low‐dose hCG vs FSH throughout the COH | RR 1.17 [0.83, 1.64] | 3 studies · 252 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Clinical pregnancy Low‐dose hCG vs FSH throughout the COH | RR 1.19 [0.92, 1.55] | 5 studies · 351 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Miscarriage Low‐dose hCG vs FSH throughout the COH | RR 1.08 [0.5, 2.31] | 4 studies · 127 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Total dose of FSH Low‐dose hCG vs FSH throughout the COH | no estimate extracted | 5 studies · 333 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency |
Oocytes retrieved Low‐dose hCG vs FSH throughout the COH | no estimate extracted | 5 studies · 333 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency |