Findings

What do systematic reviews say?

8 questions · 8 findings · 5 reviews

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No studies found 3 · 37.5%GRADE not reported 1 · 12.5%Very low 2 · 25%Low 0 · 0%Moderate 1 · 12.5%High 1 · 12.5%

Vitamin D vs placebo

Serious adverse events · premenopausal women (age 18–32.7 years)

The review found no eligible studies for this question.

1 finding from 1 review

Calcium and vitamin D for increasing bone mineral density in premenopausal women 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Vitamin D vs placebo or no intervention

Serious adverse events · people with chronic liver diseases

1 finding from 1 review

Vitamin D supplementation for chronic liver diseases in adults 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Vitamin D vs placebo or no intervention

Non‐serious adverse events · people with chronic liver diseases

1 finding from 1 review

Vitamin D supplementation for chronic liver diseases in adults 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Vitamin D plus calcium vs placebo

Serious adverse events · premenopausal women (ages 18–36 years)

The review found no eligible studies for this question.

1 finding from 1 review

Calcium and vitamin D for increasing bone mineral density in premenopausal women 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Vitamin D vs placebo or usual care

Serious adverse events · individuals with moderate to severe disease

The review found no eligible studies for this question.

1 finding from 1 review

Vitamin D supplementation for the treatment of COVID‐19: a living systematic review 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Vitamin D vs placebo

Proportion of participants with one or more serious adverse events due to any cause · children and adults with predominantly mild to moderate asthma

Summary of findings table ‐ Vitamin D showed no clear difference in proportion of participants with one or more serious adverse events… compared with placebo (high certainty).

1 finding from 1 review

Vitamin D for the management of asthma 2023 · Cochrane Headline outcomes only
OR 0.89 [0.56, 1.41]
12 studies · 1556 participants
High

Vitamin E (capsules 2000 IU/day in two divided doses) vs placebo

Number of participants experiencing any serious adverse events · people with Alzheimer's disease

Vitamin E (capsules 2000 IU/day in two divided doses) showed no clear difference in adverse events Number of participants reporting ≥ 1 serious adverse… compared with placebo (moderate certainty).

1 finding from 1 review

Vitamin E for Alzheimer's dementia and mild cognitive impairment 2017 · Cochrane Headline outcomes only
RR 0.86 [0.71, 1.05]
1 study · 304 participants
Moderate

Vitamin E (capsules 2000 IU/day in two divided doses) vs placebo

Number of participants experiencing any serious adverse events · MCI

1 finding from 1 review

Vitamin E for Alzheimer's dementia and mild cognitive impairment 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 516 participants
GRADE not reported