Relief of burning/discomfort (symptom relief; pain intensity) · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
It is very uncertain whether dietary supplements (alpha lipoic acid +/- vitamins) changes relief of burning/discomfort (symptom relief; pain intensity) compared with placebo (very low certainty).
1 finding from 1 review
Relief of burning/discomfort (symptom relief; pain intensity) · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
1 finding from 1 review
Interventions for treating burning mouth syndrome 2016 · Cochrane All outcomesshort-term (up to 3 months)
SoF5 Dietary supplements vs placebo. Symptom relief short-term: insufficient or contradictory evidence regarding benefit of any evaluated dietary supplement; 628 participants (12 RCTs); very low. Subgroups: ALA without…
12 studies · 628 participants
Very low
sUA reduction · participants with chronic gout and sUA level > 0.36mmol/L
1 finding from 1 review
Joint pain reduction ‐ not reported · participants with chronic gout and sUA level > 0.36mmol/L
The review found no eligible studies for this question.
1 finding from 1 review
Participant global assessment · participants with chronic gout and sUA level > 0.36mmol/L
The review found no eligible studies for this question.
1 finding from 1 review
Total adverse events · participants with chronic gout and sUA level > 0.36mmol/L
1 finding from 1 review
Tophus regression · participants with chronic gout and sUA level > 0.36mmol/L
The review found no eligible studies for this question.
1 finding from 1 review
Acute gout attacks · participants with chronic gout and sUA level > 0.36mmol/L
The review found no eligible studies for this question.
1 finding from 1 review
Withdrawals due to adverse events · participants with chronic gout and sUA level > 0.36mmol/L
1 finding from 1 review
Stillbirth · pregnant women receiving vitamin E supplementation or control, living in areas where there is either inadequate dietary intake of vitamin…
Any vitamin E supplementation showed no clear difference in stillbirth compared with placebo, no placebo or other supplements (moderate certainty).
1 finding from 1 review
Preterm birth · pregnant women receiving vitamin E supplementation or control, living in areas where there is either inadequate dietary intake of vitamin…
Any vitamin E supplementation showed no clear difference in preterm birth (less than 37 weeks' gestation) compared with placebo, no placebo or other supplements (high certainty).
1 finding from 1 review
Pre‐eclampsia · pregnant women receiving vitamin E supplementation or control, living in areas where there is either inadequate dietary intake of vitamin…
Any vitamin E supplementation showed no clear difference in clinical pre‐eclampsia (random‐effects model) compared with placebo, no placebo or other supplements (moderate certainty).
1 finding from 1 review
Intrauterine growth restriction · pregnant women receiving vitamin E supplementation or control, living in areas where there is either inadequate dietary intake of vitamin…
Any vitamin E supplementation showed no clear difference in intrauterine growth restriction (various definitions) compared with placebo, no placebo or other supplements (high certainty).
1 finding from 1 review
Preterm prelabour rupture of membranes · pregnant women receiving vitamin E supplementation or control, living in areas where there is either inadequate dietary intake of vitamin…
Any vitamin E supplementation showed no clear difference in prelabour rupture of fetal membranes ‐ preterm compared with placebo, no placebo or other supplements (low certainty).
1 finding from 1 review
Bleeding episodes (placental abruption) · pregnant women receiving vitamin E supplementation or control, living in areas where there is either inadequate dietary intake of vitamin…
Any vitamin E supplementation leads to lower bleeding episodes (placental abruption) compared with placebo, no placebo or other supplements (high certainty).
1 finding from 1 review